the NSF of China (20672089, 20832005);the NFFTBS (J1030415);the National Basic Research Program of China (973 Program, 2010CB833200)
Starting from the oxygenated piperidine building block 20,two synthetic approaches to new building blocks (8R,8aS)-and (8R,8aR)-8-hydroxy-5-indolizidinones 19a/19b and 15a/15b have been developed,respectively. The fir...