The first two authors contributed equally to this study Acknowledgements This work was supported by grants from the National Natural Science Foundation of China (No. 30471988, 30873027, 30901784 and No.30330610) and Postdoctoral Science Foundation of China (No.2005038259).
Objective: To construct the gene of a recombinant anti-HER2 fusion protein, ScFv/tBid, and investigate its pro-apopotic effect on osteosarcoma E10 cell line. Methods: Firsl, the expression of HER-2 in El0 cells was ...