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作品数:8被引量:4H指数:1
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相关期刊:《Molecular Plant》《Journal of Agricultural Science and Technology(A)》《Journal of Integrative Plant Biology》《Cell Research》更多>>
相关基金:国家自然科学基金霍英东教育基金更多>>
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Structural basis of prokaryotic NAD-RNA decapping by NudC被引量:1
《Cell Research》2016年第9期1062-1066,共5页Delin Zhang Yexmg Liu Qiang Wang Zeyuan Guan Jing Wang Jian Liu Tingting Zou Ping Yin 
In eukaryotes, the 5′,5′-triphosphate-linked 7-meth- ylguanosine (mTG) cap is essential for modulation of mRNA metabolism and protects the mRNA from degradation [1]. Removal of the cap from the 5′-terminus of the...
Lsm2 and Lsm3 bridge the interaction of the Lsml-7 complex with Pat1 for decapping activation被引量:1
《Cell Research》2014年第2期233-246,共14页Donghui Wu Denise Muhlrad Matthew W Bowler Shimin Jiang Zhou Liu Roy Parker Haiwei Song 
We thank the beamline scientists at ID14-4 and ID23-1 (ESRF, France), PXI (SLS, Switzerland), BL13B1 (NSRRC, Taiwan) and BL17U (SSRF, Shanghai, China) for assistance and access to syn- chrotron radiation facilities. This work was financially supported by the Agency for Science, Technology and Research in Singapore (HS) and partly by the National Natural Science Foundation of China (31270816) and Zhejiang Provincial Natural Science Fu- oundation of China (LZ 12C05001).
The evolutionarily conserved Lsml-7-Patl complex is the most critical activator of mRNA decapping in eukaryotic cells and plays many roles in normal decay, AU-rich element-mediated decay, and miRNA silencing, yet how ...
关键词:mRNA decay decapping activation LSM Patl x-ray crystallography 
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