supported by the Chinese Academy of Sciences (Grant Nos. E4V4061 and E2VK311);supported by the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences (Grant No. 2021-I2M-1-037);supported by the National Natural Science Foundation of China (Grant Nos. 81971985 and 82272308).
Most phages—viruses infecting prokaryotes—inject their genomes via a tail structure.The central tail tube,composed of tail tube protein(TTP),typically forms conserved hexameric or trimeric rings.In this paper,we rep...