FARNESYLATION

作品数:5被引量:39H指数:3
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相关领域:医药卫生更多>>
相关期刊:《Molecular Plant》《Journal of Integrative Plant Biology》《Science China(Life Sciences)》《World Journal of Gastroenterology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划高等学校学科创新引智计划更多>>
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Protein prenylation and human diseases: a balance of protein farnesylation and geranylgeranylation被引量:8
《Science China(Life Sciences)》2015年第4期328-335,共8页XU Na SHEN Ning WANG XiuXing JIANG Shan XUE Bin LI ChaoJun 
supported by the National Basic Research Program of China(2012CB524900,2009CB918703);National Natural Science Foundation of China(31271540,30671086)awarded to Li Chao Jun
The protein prenylation is one of the essential post-translational protein modifications, which extensively exists in the eukaryocyte. It includes protein farnesylation and geranylgeranylation, using farnesyl pyrophos...
关键词:protein prenylation GGPP FPP biological function regulation 
Role of abnormal lipid metabolism in development,progression,diagnosis and therapy of pancreatic cancer被引量:19
《World Journal of Gastroenterology》2014年第9期2279-2303,共25页Julian Swierczynski Areta Hebanowska Tomasz Sledzinski 
Supported by Medical University of Gdansk Grants ST-41,ST-40
There is growing evidence that metabolic alterations play an important role in cancer development and progression.The metabolism of cancer cells is reprogrammed in order to support their rapid proliferation.Elevated f...
关键词:Pancreatic cancer  Lipid metabolism  Fatty acid synthase  Monounsaturated fatty acids  Farnesylation  Hypoxia inducible factor    Cyclooxygenase-2  Oncogenes  Tumor suppressors  Lipogenic enzymes inhibitors 
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