Supported by the National Natural Science Foundation:Based on Serum Fingerprint to Develop a New Method for Preparing Serum Containing Drugs(No.81403282);the Natural Science Foundation of Beijing Municipality:Influence of Intestinal First-Pass Effect on the Curing Effect of Traditional Chinese Medicine(No.7133251)
OBJECTIVE:To study the absorption and biotransformation of liquiritin,cinnamic acid,paeoniflorin,and glycyrrhizic acid in the Guizhi decoction (GZD) in the gastrointestinal tracts of rats.METHODS:A simple and reliable...