by National Science and Technology Major Project,No.2017ZX10302201,No.2017ZX09304004 and No.2014ZX10002002;National Program on Key Basic Research Project(973 Program),No.2015CB554304.
BACKGROUND Quantitative hepatitis B core-related antigen(qHBcrAg)has a better correlation with intrahepatic hepatitis B virus(HBV)covalently closed circular DNA(cccDNA)than HBV DNA or hepatitis B e antigen(HBeAg),but ...
supported by the National Basic Research Program of China (Grant Nos. 2005CB522902 and 2007CB512900);the National High Technology Research and Development Program of China (Grant No. 2006AA02A410);the National Natural Science Foundation of China (Grant No. 30901256);the Beijing Natural Science Foundation (Grant No. 7102153);National Science and Technology Major Project for Infectious Diseases Control During the 11th Five-Year Plan Period (Grant Nos. 2008ZX10002-012 and 2008ZX10002-013);Peking University People’s Hospital Research Development Funds (Grant No. RDC 2009-13);Key Clinical Research Program of Ministry of Health of China
The efficacy of interferon (IFN) is limited in about 1/3 of patients with chronic hepatitis B (CHB). We used two-dimensional electrophoresis (2-DE)-based proteomic strategies to identify potential serum markers predic...