Supported by the National Natural Science Foundation of China,No.81174263;National Science and Technology Major Project during the 12th Five-year Plan Period,No.2012ZX1005006;Sanming Project of Medicine in Shenzhen,Guangdong Province,China,No.SZSM201612074;and Science and Technology Planning Project of Guangdong Province,China,No.2017A020213016.
BACKGROUND No guideline recommends antiviral therapy for hepatitis B e antigen(HBeAg)-positive chronic hepatitis B patients with persistently normal alanine aminotransferase levels and a high hepatitis B virus(HBV)DNA...
BACKGROUND: Hepatitis B virus (HBV) infection, a glo- bal public health problem, is the leading cause of cirrhosis and hepatocellular carcinoma (HCC) worldwide. There are more than 350 million HBV carriers in the worl...