G-QUADRUPLEXES

作品数：14被引量：18H指数：2
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Interaction between human telomeric G-quadruplexes characterized by single molecule magnetic tweezers
《Chinese Physics B》2018年第6期543-553,共11页Yi-Zhou Wang Xi-Miao Hou Hai-Peng Ju Xue Xiao Xu-Guang Xi Shuo-Xing Dou Peng-Ye Wang Wei Li 
supported by the National Natural Science Foundation of China(Grant Nos.11474346 and 11774407);the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(Grant No.QYZDB-SSW-SLH045);the National Key Research and Development Program,China(Grant No.2016YFA0301500)
Human telomeric G-quadruplex plays a crucial role in regulating the genome stability. Despite extensive studies on structures and kinetics of monomeric G-quadruplex, the interaction between G-quadruplexes is still in ...
关键词：BIOPHYSICS G-QUADRUPLEXES single-molecule studies DNA structures 
Bloom's syndrome protein unfolding G-quadruplexes in two pathways
《Chinese Physics B》2017年第8期561-564,共4页赵振业 徐春华 史婧 李菁华 马建兵 贾棋 马东飞 李明 陆颖 
supported by the National Natural Science Foundation of China(Grant Nos.11674382,11574381,and 11574382);the Key Research Program of Frontier Sciences,Chinese Academy of Sciences(Grant No.QYZDJ-SSW-SYS014)
The Bloom helicase （BLM） gene product encodes a DNA helicase that functions in homologous recombination repair to prevent genomic instability. BLM is highly active in binding and unfolding G-quadruplexes （G4）, whi...
关键词：G-QUADRUPLEXES BLM HELICASE smFRET 
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