supported by the National Natural Science Foundation of China(21732002,22077043,31672558,31871305,21907036);Opening Foundation of State Key Laboratory of Freshwater Ecology and Biotechnology,China(2020FB08);the Fundamental Research Funds for the(2662018PY021,2662019PY003,2662020PY001);Huazhong Agricultural University Scientific&Technological Self-innovation Foundation(2016RC011);HZAU-AGIS Cooperation Fund(SZYJY2021010)。
G-quadruplexes in viral genomes can be applied as the targets of antiviral therapies, which has attracted wide interest. However, it is still not clear whether the pervasive number of such elements in the viral world ...