G-QUADRUPLEXES

作品数:14被引量:18H指数:2
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相关期刊:《Science China Chemistry》《Chinese Physics B》《Signal Transduction and Targeted Therapy》《Chemical Research in Chinese Universities》更多>>
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DNA G-Quadruplexes as Targets for Natural Product Drug Discovery
《Engineering》2024年第7期39-51,共13页Kai-Bo Wang Yingying Wang Jonathan Dickerhoff Danzhou Yang 
supported by the National Institutes of Health(R01CA177585,U01CA240346,and R01CA153821)(DY);the Purdue Center for Cancer Research(P30CA023168);the National Natural Science Foundation of China(82173707 and 82322065);the Program for Jiangsu Province Innovative Research Scholar(JSSCRC2021512);the“Double First-Class”University Project(CPUQNJC22_08).
DNA guanine(G)-quadruplexes(G4s)are unique secondary structures formed by two or more stacked Gtetrads in G-rich DNA sequences.These structures have been found to play a crucial role in highly transcribed genes,especi...
关键词:G-QUADRUPLEX Natural products ALKALOIDS CANCER PROMOTER 
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