supported by the National Science and Technology Major Project [2018ZX10713-002,2017ZX10104001,2018ZX10711001];National key research and development project [2017YFC1200505,2016YFC1200905];the Development Grant of State Key Laboratory of Infectious Disease Prevention and Control [2015SKLID505,2014SKLID103]
Objective The current outbreak of Zika virus(ZIKV)poses a severe threat to human health.Two ZIKV strains were isolated from mosquitoes collected from the Dejiang prefecture in China in 2016,which was the first isolati...
supported by the National Key Program for Infectious Diseases of China (2009ZX10004-4001)
Objective LcrV is an important component for the development of a subunit vaccine against plague.To reduce immunosuppressive activity of LcrV,a recombinant LcrV variant lacking amino acids 271 to 326 (rV270) was pre...