Herpes simplex virus (HSV), the viral agent causing human genital herpes, recurs easily and poses significant harm to patients, while also being associated with atherosclerosis (AS). Currently, no effective therapy or...
supported by the Fujian Natural Science Foundation Project(General)[Grant number:2021J011265];the Fund for Scientific Research Projects of the Organ Transplantation Section of the Joint Logistics Support Force Key Discipline of Joint Logistics Medicine[Grant number:LQZDQG].
Background and Aims:Hepatocellular carcinoma(HCC)is one of the most fatal malignancies.Epigenetic mechanisms have revealed that noncoding RNAs,such as microRNAs(miRNAs)and circular RNAs(circRNAs),are involved in HCC p...
Acute leukemia is an aggressive disease that has high mortality rates worldwide.The error rate can be as high as 40%when classifying acute leukemia into its subtypes.So,there is an urgent need to support hematologists...
supported by the grants from the National Key R&D Program of China(No.2019YFA0906000);the Guangdong Basic and Applied Basic Research Foundation(No.2020A1515110032);Guangdong Provincial Key Laboratory of Synthetic Genomics(No.2019B030301006);Shenzhen Key Laboratory of Synthetic Genomics(No.ZDSYS201802061806209);Shenzhen Institute of Synthetic Biology Scientific Research Program(Nos.HSY899011058,HSE199011345,and HSE199011058).
The autoantibody in patients’serum can act as a biomarker for diagnosing cancer,and the differences in autoantibodies are significantly correlated with the changes in their target proteins.In this study,16 renal canc...
MicroRNAs (miRNAs) are a functional small non-coding RNA and play essential roles in gene regulation indevelopment, differentiation and proliferation. In order to investigate the miRNAs function in Lewis rat hippocamp...
funded by National Natural Science Foundation of China(Grant No.61975056;)the Shanghai Natural Science Foundation(Grant No.19ZR1416000);the Science and Technology Commission of Shanghai Municipality(Grants No.20440713100,19511120100,18DZ2270800).
The incidence of breast cancer is tending younger globally,and tumor development,clinical treatment,and prognosis are largely influenced by histopathological diagnosis.For diagnosed patients,the distinction between th...
We performed a bioinformatics analysis with validation by multiple databases,aiming to evaluate the diagnostic and prognostic value of Kelch-like ECH-associated protein 1(Keapl)mRNA for lung cancer,and to explore poss...
This study was funded by the National Natural Science Foundation of China(grant no.81972559)and the Shanghai Shenkang Hospital Development Center Project(project no.HDC2020CR2067B).
Objective To identify novel biomarkers and therapeutic targets for primary melanoma using network-based microarray data analysis.Methods Eligible microarray datasets from the Gene Expression Omnibus(GEO)database were ...
a grant from the Special Medicine Innovation Scientific Special Project(No.2018ZX09733003)。
Multiple myeloma(MM)is a blood malignancy characterized by the clonal proliferation of plasma cells,which increases the number of monoclonal immunoglobulins in blood and urine and causes target organ damage.Long non-c...
Background:CD4+CD25+Foxp3+regulatory T cells are essential for immune homeostasis.Naive Treg cells can undergo further differentiation into an effector state in response to antigen and a variety of environment cues.Ho...