MICROARRAY

作品数:440被引量:1533H指数:15
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相关领域:医药卫生生物学更多>>
相关作者:范保星吴德昌张开泰石磊黄圆更多>>
相关机构:清华大学复旦大学军事医学科学院北京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划国家教育部博士点基金更多>>
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  • 学科=医药卫生—肿瘤x
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Differential Expressed Genes in ECV304 Endothelial-Like Cells Infected with Herpes Simplex Virus Type 2
《Journal of Biosciences and Medicines》2024年第11期407-432,共26页Yuqi Xu Meiling Gong Wenling Zheng Wenli Ma Yali Zhang Xiaoyang Mo Huanying Zheng Changwen Ke Meilan Liu Diaodiao Shi Hui Zhang Haiquan Zhao Yaqiong Ye 
Herpes simplex virus (HSV), the viral agent causing human genital herpes, recurs easily and poses significant harm to patients, while also being associated with atherosclerosis (AS). Currently, no effective therapy or...
关键词:HSV-2 ECV304 Cells MICROARRAY 
Identification and Validation of the Hsa_circ_0001726/miR-140-3p/KRAS Axis in Hepatocellular Carcinoma Based on Microarray Analyses and Experiments
《Journal of Clinical and Translational Hepatology》2024年第11期897-906,共10页Xiaobin Chi Zhijian Chen Jianda Yu Xiaohua Xie Zerun Lin Yongbiao Chen Lizhi Lv 
supported by the Fujian Natural Science Foundation Project(General)[Grant number:2021J011265];the Fund for Scientific Research Projects of the Organ Transplantation Section of the Joint Logistics Support Force Key Discipline of Joint Logistics Medicine[Grant number:LQZDQG].
Background and Aims:Hepatocellular carcinoma(HCC)is one of the most fatal malignancies.Epigenetic mechanisms have revealed that noncoding RNAs,such as microRNAs(miRNAs)and circular RNAs(circRNAs),are involved in HCC p...
关键词:Circular RNA microRNA PROGNOSIS Hepatocellular cancer BIOINFORMATICS Tyrosine kinase inhibitor 
A Survey on Acute Leukemia Expression Data Classification Using Ensembles
《Computer Systems Science & Engineering》2023年第11期1349-1364,共16页Abdel Nasser H.Zaied Ehab Rushdy Mona Gamal 
Acute leukemia is an aggressive disease that has high mortality rates worldwide.The error rate can be as high as 40%when classifying acute leukemia into its subtypes.So,there is an urgent need to support hematologists...
关键词:LEUKEMIA CLASSIFICATION ENSEMBLE rotation forest pairwise correlation bayesian networks gene expression data MICROARRAY gene selection 
Screening of autoantibodies as biomarkers in the serum of renal cancer patients based on human proteome microarray被引量:2
《Acta Biochimica et Biophysica Sinica》2022年第12期1909-1916,共8页Yangyang Sun Chengxi Liu Huidong Zhong Chenguang Wang Haibo Xu Wei Chen 
supported by the grants from the National Key R&D Program of China(No.2019YFA0906000);the Guangdong Basic and Applied Basic Research Foundation(No.2020A1515110032);Guangdong Provincial Key Laboratory of Synthetic Genomics(No.2019B030301006);Shenzhen Key Laboratory of Synthetic Genomics(No.ZDSYS201802061806209);Shenzhen Institute of Synthetic Biology Scientific Research Program(Nos.HSY899011058,HSE199011345,and HSE199011058).
The autoantibody in patients’serum can act as a biomarker for diagnosing cancer,and the differences in autoantibodies are significantly correlated with the changes in their target proteins.In this study,16 renal canc...
关键词:renal cancer AUTOANTIBODY BIOMARKER human proteome microarray 
Microarray Analysis of MicroRNA Expression Profiles in Newborn and Adult Rats Hippocampus
《Yangtze Medicine》2022年第2期24-40,共17页Jia Yang Yueyang Yu Zhengze Zhang Bo Su Yun Zheng Yang Liu 
MicroRNAs (miRNAs) are a functional small non-coding RNA and play essential roles in gene regulation indevelopment, differentiation and proliferation. In order to investigate the miRNAs function in Lewis rat hippocamp...
关键词:MICRORNA MICROARRAY HIPPOCAMPUS DEVELOPMENT 
PCA-U-Net based breast cancer nest segmentation from microarray(jj)hyperspectral images被引量:2
《Fundamental Research》2021年第5期631-640,共10页Jiansheng Wang Yan Wang Xiang Tao Qingli Li Li Sun Jiangang Chen Mei Zhou Menghan Hu Xiufeng Zhou 
funded by National Natural Science Foundation of China(Grant No.61975056;)the Shanghai Natural Science Foundation(Grant No.19ZR1416000);the Science and Technology Commission of Shanghai Municipality(Grants No.20440713100,19511120100,18DZ2270800).
The incidence of breast cancer is tending younger globally,and tumor development,clinical treatment,and prognosis are largely influenced by histopathological diagnosis.For diagnosed patients,the distinction between th...
关键词:Microscopic hyperspectral imaging Breast cancer Tissue microarrays Deep learning 
Diagnostic and Prognostic Significance of Keapl mRNA Expression for Lung Cancer Based on Microarray and Clinical Information from Oncomine Database
《Current Medical Science》2021年第3期597-609,共13页Guang-ya LIU Wei ZHANG Xu-chi CHEN Wen-juan WU Shi-qian WAN 
We performed a bioinformatics analysis with validation by multiple databases,aiming to evaluate the diagnostic and prognostic value of Kelch-like ECH-associated protein 1(Keapl)mRNA for lung cancer,and to explore poss...
关键词:Kelch-like ECH-associated protein 1 lung cancer receiver operating characteristic curve analysis Cox regression CO-EXPRESSION signaling pathway 
Re-Exploring Biomarkers and Therapeutic Targets in Primary Melanoma Patients: Insights from Network-Based Analysis of Microarray Data
《Chinese Journal of Plastic and Reconstructive Surgery》2020年第4期228-240,共13页Kangjie SHEN Chuanyuan WEI Yi XIE Lu WANG Shuyu WANG Ming REN Xinyi DENG Daohe WANG Zixu GAO Zihao FENG Jianying GU 
This study was funded by the National Natural Science Foundation of China(grant no.81972559)and the Shanghai Shenkang Hospital Development Center Project(project no.HDC2020CR2067B).
Objective To identify novel biomarkers and therapeutic targets for primary melanoma using network-based microarray data analysis.Methods Eligible microarray datasets from the Gene Expression Omnibus(GEO)database were ...
关键词:MELANOMA Network-based analysis MICROARRAY Centromere protein F Biomarkers 
Competing endogenous RNA network in newly diagnosed multiple myeloma by genetic microarray
《Chinese Medical Journal》2020年第21期2619-2621,共3页Yu-Qin He Zhi-Yao Zhang Hui-Xing Zhou Fang Ye Wen-Ming Chen 
a grant from the Special Medicine Innovation Scientific Special Project(No.2018ZX09733003)。
Multiple myeloma(MM)is a blood malignancy characterized by the clonal proliferation of plasma cells,which increases the number of monoclonal immunoglobulins in blood and urine and causes target organ damage.Long non-c...
关键词:ENDOGENOUS expression. MYELOMA 
TIGIT+ immunoregulatory T cells upregulate autophagy-related proteins
《Tumor Microenvironment Research》2020年第3期79-86,共8页Bo-Zhao Ma 
Background:CD4+CD25+Foxp3+regulatory T cells are essential for immune homeostasis.Naive Treg cells can undergo further differentiation into an effector state in response to antigen and a variety of environment cues.Ho...
关键词:Bioinformatics analysis TIGIT-Treg TIGIT+Treg MICROARRAY Differentially expressed genes 
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