SINGLE-DOMAIN

作品数：19被引量：12H指数：2
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相关期刊：《Journal of Wuhan University of Technology(Materials Science)》《Science China(Life Sciences)》《Acta Pharmacologica Sinica》《Journal of Bio-X Research》更多>>
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Generation and antitumor effects of an engineered and energized fusion protein VL-LDP-AE composed of single-domain antibody and lidamycin被引量：3
《Science China(Life Sciences)》2007年第4期447-456,共10页MIAO QingFang, SHANG BoYang, OUYANG ZhiGang, LIU XiaoYun & ZHEN YongSu Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China 
Supported by the National High Technology Research and Development Program of China (863 Program)(Grant No. 2006AA02A255)
Type IV collagenase plays a pivotal role in invasion, metastasis and angiogenesis of tumor. Single domain antibodies are attractive as tumor-targeting vehicle because of their much smaller size com-pared with antibody...
关键词：type IV COLLAGENASE SINGLE-DOMAIN ANTIBODY LIDAMYCIN fusion protein antibody-based drugs 
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