This work was supported by the National Natural Science Foundation of China(21702091);Science and Technology Innovation Development Plan of Yantai(2020MSGY114);Yantai“Double Hundred Plan”;The authors also thank the Talent Induction Program for Youth Innovation Teams in Colleges and Universities of Shandong Province;The Graduate Innovation Foundation of Yantai University(YDYB2128)is gratefully acknowledged(for Y.-J.Hu).
An I_(2)-mediated[3+2]annulation of methyl-azaarenes with alkyl_(2)-isocyanoacetates or amino acid ester hydrochlorides has been demonstrated.This strategy involves CuN bond cleavage of isocyanides and can selectively...
This work was supported by the National Natural Science Foundation of China(21702091);the Science and Technology Innovation Development Plan of Yantai(2020MSGY114);the Yantai“Double Hundred Plan”.
A high-efficiency strategy for the synthesis of furoxans and 1,2,4-oxadiazoles has been developed,using tert-butyl nitrite(TBN)as the nitrogen source.Azaarene nitrile oxides as activated intermediates were generated i...