Background:Uremic pruritus is one of the most common disabling problems in patients with chronic renal failure.Few studies have evaluated itching and cutaneous manifestations in hemodialysis-dependent patients.Objecti...
Background: Changes in the large vessels and microcirculation of the diabetic foot are important in the development of foot ulceration and subsequent failure to heal existing ulcers. We investigated whether oxygen del...
People with diabetes develop foot ulcers because of neuropathy (sensory, motor, and autonomic deficits), ischaemia, or both. The initiating injury may be from acute mechanical or thermal trauma or from repetitively or...
Objective: To determine the efficacy and safety of short- contact administration of topical tretinoin on foot ulcers in patients with diabetes. Design: Randomized, double- blind, placebocontrolled trial. Setting: Outp...
Diabetic and ischaemic non- healing pedal ulcers have a tendency for chronicity and increased chances of infection, which may threaten the viability of the foot. Systemic administration of therapeutic agents may be in...
Context:Among persons diagnosed as having diabetes mellitus, the prevalence of foot ulcers is 4%to 10%, the annual population-based incidence is 1.0%to 4.1 %, and the lifetime incidence may be as high as 25%. These ul...