Sera from paraneoplastic pemphigus (PNP) immunoprecipitate multiple antigens from human epidermal protein extract. In this study, we further characterized the autoantibodies in 12 PNP sera. Immunoblotting using recomb...
Background: Paraneoplastic pemphigus (PNP) is an autoimmune mucocutaneous disease. We previously reported that B cells in a Castleman tumour associated with PNP produced autoantibodies. However, it is uncertain whethe...
Background:Neoplasia-induced lichen planus is described as a cell-mediated reaction to unknown epithelial antigens. Para-neoplastic pemphigus (PNP), characterized by the presence of a specific array of autoantibodies,...
Paraneoplastic pemphigus is a life- threatening auto- immune bullous disease associated with neoplasia, generally of lymphoid origin. Immunosuppressive therapy is often disappointing and there are only a few reports o...
Background: Most paraneoplastic pemphigus (PNP) cases reported to date have been associated with lymphoproliferative neoplasms. Patients with PNP have autoantibodies against the plakin family (eg, envoplakin and perip...