Β-ARRESTIN

作品数：202被引量：555H指数：11
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相关领域：医药卫生更多>>
相关作者：范恒魏伟汪庆童邹琳马兰更多>>
相关机构：华中科技大学安徽医科大学中国科学院上海生命科学研究院重庆医科大学更多>>
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相关基金：国家自然科学基金国家教育部博士点基金国家重点基础研究发展计划中国博士后科学基金更多>>
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Exploring a novel mechanism for targeting β-arrestin-2 in the management of diabetic nephropathy
《World Journal of Diabetes》2025年第4期1-7,共7页Na Liu Wei-Tao Yan Kun Xiong 
Supported by National Natural Science Foundation of China,No.82303047,No.82372507,No.82172196 and No.32401046;Natural Science Foundation of Hunan Province,No.2022JJ40801。
Diabetic nephropathy(DN)is a well-known microvascular complication in patients with diabetes mellitus,which is characterized by the accumulation of extracellular matrix in the glomerular and tubulointerstitial compart...
关键词：Diabetes mellitus Diabetic nephropathy β-arrestin-2 Endoplasmic reticulum stress ATF6 signaling pathway 
From metabolic regulation to kidney protection: β-arrestin 2 as a dual-function therapeutic target
《World Journal of Diabetes》2025年第3期273-276,共4页Jian Yang Cheng-Zhi Zhang Jing Zhang 
Supported by National Natural Science Foundation of China,No.82471616,No.82170418,and No.82271618;Natural Science Foundation of Hubei Province,No.2022CFA015;Central Guiding Local Science and Technology Development Project,No.2022BGE237;Key Research and Development Program of Hubei Province,No.2022BCE001,and No.2023BCB139;Hubei Provincial Health Commission Project,No.WJ2023M151。
We are deeply interested in the recent findings onβ-arrestin 2.Liu et al demonstrated thatβ-arrestin 2 knockout provides significant protection in diabetic nephropathy,underscoring its potential as a promising thera...
关键词：Type 2 diabetes Diabetic nephropathy β-arrestin 2 β-arrestin 1 Metabolic regulation Tissue-specific signaling Therapeutic strategies Multi-target therapies 
β-Arrestin-2 enhances endoplasmic reticulum stress-induced glomerular endothelial cell injury by activating transcription factor 6 in diabetic nephropathy被引量：2
《World Journal of Diabetes》2024年第12期2322-2337,共16页Jiang Liu Xiao-Yun Song Xiu-Ting Li Mu Yang Fang Wang Ying Han Ying Jiang Yu-Xin Lei Miao Jiang Wen Zhang Dong-Qi Tang 
Supported by Key Research and Development Program of Shandong Province,No.2021CXGC011101;Special Fund for Taishan Scholars Project,No.tsqn202211324;National Natural Science Foundation of China,No.81900669;Natural Science Foundation of Shandong Province,China,No.ZR2018PH007;the Multidisciplinary Innovation Center for Nephrology of the Second Hospital of Shandong University.
BACKGROUND Glomerular endothelial cell(GENC)injury is a characteristic of early-stage diabetic nephropathy(DN),and the investigation of potential therapeutic targets for preventing GENC injury is of clinical importanc...
关键词：Diabetic nephropathy Glomerular endothelial cell β-Arrestin-2 Activating transcription factor 6 Endoplasmic reticulum stress 
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