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作品数：219被引量：501H指数：11
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Significant Histologic Changes Are Not Rare in Treatment-naive Hepatitis B Patients with Normal Alanine Aminotransferase Level:A Meta-analysis被引量：6
《Journal of Clinical and Translational Hepatology》2021年第5期615-625,共11页Chi Zhang Jia-Wen Li Zhao Wu Hong Zhao Gui-Qiang Wang 
This study was supported by the China Mega-Project for Infectious Diseases(Grant Nos.2017ZX10203202 and 2013ZX10002005);the China Mega-Project for Innovative Drugs(Grant No.2016ZX09101065).
Background and Aims:Chronic hepatitis B is the main cause of liver cancer.However,the most neglected group has been treatment-naive chronic hepatitis B patients with normal alanine aminotransferase(ALT).People have te...
关键词：Significant histologic changes Chronic hepatitis B Normal ALT META-ANALYSIS 
Efficacy and Safety of 12-week Interferon-based Danoprevir Regimen in Patients with Genotype 1 Chronic Hepatitis C被引量：13
《Journal of Clinical and Translational Hepatology》2019年第3期221-225,共5页Lai Wei Jia Shang Yuanji Ma Xiaoyuan Xu Yan Huang Yujuan Guan Zhongping Duan Wenhong Zhang Zhiliang Gao Mingxiang Zhang Jun Li Jidong Jia Yongfeng Yang Xiaofeng Wen Maorong Wang Zhansheng Jia Bo Ning Yongping Chen Yue Qi Jie Du Jianning Jiang Lixin Tong Yao Xie Jinzi JWu 
Ascletis Pharmaceuticals Co.,Ltd.provided financial support for this study(MANASA)
Background and Aims:Genotype(GT)1 remains the predominant hepatitis c virus(HCV)GT in Chinese patients.Over 80%of those Chinese patients harbor the interferon-sensitive CC allele of IFNL4rs12979860,which is favorable ...
关键词：Danoprevir Hepatitis C virus(HCV) Sustained virological response(SVR) Treatment-naive 
Efficacy and Safety of All-oral,12-week Ravidasvir Plus Ritonavir-boosted Danoprevir and Ribavirin in Treatment-naive Noncirrhotic HCV Genotype 1 Patients:Results from a Phase 2/3 Clinical Trial in China被引量：15
《Journal of Clinical and Translational Hepatology》2019年第3期213-220,共8页Xiaoyuan Xu Bo Feng Yujuan Guan Sujun Zheng Jifang Sheng Xingxiang Yang Yuanji Ma Yan Huang Yi Kang Xiaofeng Wen Jun Li Youwen Tan Qing He Qing Xie Maorong Wang Ping An Guozhong Gong Huimin Liu Qin Ning Rui Hua Bo Ning Wen Xie Jiming Zhang Wenxiang Huang Yongfeng Yang Minghua Lin Yingren Zhao Yanhong Yu Jidong Jia Dongliang Yang Liang Chen Yinong Ye Yuemin Nan Zuojiong Gong Quan Zhang Peng Hu Fusheng Wang Yongguo Li Dongliang Li Zhansheng Jia Jinlin Hou Chengwei Chen Jinzi JWu Lai Wei 
Ascletis BioScience Co.,Ltd.provided financial support for this study
Background and Aims:Ravidasvir(RDV)is a new generation pangenotypic hepatitis C virus(HCV)NS5A inhibitor,with high barrier to baseline resistance-associated species.This is the first phase 2/3 study conducted in China...
关键词：Ravidasvir Danoprevir HCV SVR Treatment-naive Noncirrhotic GT1 
Occult HCV Infection (OCI) Diagnosis in Cirrhotic and Non-cirrhotic Naive Patients by Intra-PBMC Nested Viral RNA PCR被引量：3
《Journal of Clinical and Translational Hepatology》2017年第4期319-326,共8页Mohamed Darwish Ahmed Abd Alla Saleh Ahmed Elibiary George Y.Wu Mostafa Kamel El-Awady 
Financial support for this study was provided by the Faculty of Medicine at Al-Azhar University,National Research Center;by the Academy of Scientific Research and Technology Development Fund(Grant No.3365,to Mostafa K El-Awady).A grant from Alexion Corp.and the Herman Lopata Chair in Hepatitis Research is gratefully acknowledged
Background and Aims:Occult HCV infections(OCIs)include IgG antibody seronegative cryptogenic(COCIs),as well as seropositive secondary na(i)ve(SNOCIs)and experienced(SEOCIs)cases.We used peripheral-blood-mononuclear-ce...
关键词：OCIs PBMCS Na(i)ve Cirrhosis 
Hepatitis C Virus RNA Strands Detection in Peripheral Blood Mononuclear Cells Legitimizes Virus Eradication in Negative Serum PCR Naive and Post-treatment Patients被引量：1
《Journal of Clinical and Translational Hepatology》2017年第1期1-8,共8页Mohamed Darwish Ahmed Abd Alla Mostafa Kamel El Awady 
Financial support for this study was provided by the Faculty of Medicine at Al-Azhar University,National Research Center;by the Academy of Scientific Research and Technology Development Fund(Grant 3365,to Mostafa K El Awady)
Background and Aims:Hepatitis C virus(HCV)hepatotropism is associated with intra-peripheral blood mononuclear cell(PBMC)infection that causes post-treatment relapse in RNA seronegative patients.Our understanding of th...
关键词：HCV PBMCS RNA STRANDS 
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