National Basic Research Program of China(973Program),No.2015CB554001;National Natural Science Foundation of China,No.81472257 and No.81502022;Natural Science Fund for Distinguished Young Scholars of Guangdong Province,No.2016A030306002;Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program,No.2015TQ01R454;Natural Science Foundation of Guangdong Province,No.2016A030310222 and No.2018A0303130303;Science and Technology Program of Guangzhou,No.201506010099 and No.2014Y2-00160;Science and Technology Program of Guangdong Province,No.2014A020215011;Fundamental Research Funds for the Central Universities(Sun Yat-sen University),No.2015ykzd10 and No.16ykpy35;Program of Introducing Talents of Discipline to Universities;National Key Clinical Discipline
BACKGROUND In recent decades, neoadjuvant therapy(NT) has been the standardized treatment for locally advanced rectal cancer(LARC). Approximately 8%-35% of patients with LARC who received NT were reported to have achi...