supported by the National Key Technology R&D Program(2012BAI31B04);the Open Project Program of National Population;Family Planning Key Laboratory of Contraceptives Drugs and Devices(2016KF08);the National Natural Science Foundation of China(81102385)
The purpose of this study is to evaluate the in vivo retention capabilities of poloxamer-based in situ hydrogels for vaginal application with nonoxinol-9 as the model drug. Two in situ hydrogel formulations, which con...