supported by the National Natural Science Foundation of China(81171049);the National Basic Research Development Program of China(2011CB504100 and2013CB835100);the National Key Technology R&D Program of China(2013BAI04B04);the Twelfth Five-Year Project of China(AWS12J004)
The α2δ-1 subunit of the voltage-gated Ca2+ channel (VGCC) is a molecular target of gabapentin (GBP), which has been used as a first-line drug for the relief of neuropathic pain. GBP exerts its anti-nociceptive...