PROTEIN-PROTEIN_INTERACTIONS

作品数：59被引量：141H指数：6
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A DNA Force Circuit for Exploring Protein-Protein Interactions at the Single-Molecule Level
《Chinese Journal of Chemistry》2024年第13期1456-1464,共9页Kangkang Ma Luoan Xiong Zhuofei Wang Xin Hu Lihua Qu Xuetong Zhao Yao Li Zhongbo Yu 
This work was supported by the National Natural Science Foundation of China[Grant 32071227 to Z.Y.,Grant 12275137 to Y.L.];Tianjin Municipal Natural Science Foundation of China(22JCYBJC01070 to Z.Y.);State Key Laboratory of Precision Measuring Technology and Instruments(Tianjin University)[Grant pilab2210 to Z.Y.].
Protein-protein interactions(PPls)play a crucial role in drug discovery and disease treatment.However,the development of effective drugs targeting PPls remains challenging due to limited methodologies for probing thei...
关键词：Single-molecule studies Protein-protein interactions Click chemistry Genetic code expansion Molecular dynamics 
Optogenetic Control of Phosphatidylinositol (3,4,5)-Triphosphate Production by Light-Sensitive Cryptochrome Proteins on the Plasma Membrane被引量：1
《Chinese Journal of Chemistry》2021年第5期1240-1246,共7页Lingzhi Yang Takeaki Ozawa Haifeng Dong Xueji Zhang 
the National Natural Science Foundation of Guangdong Province project(No.2018A030310579);the Medical Research Foundation of Guangdong Province project(No.A2019024);CREST(No.JPMJCR1752 to T.O.)from Japan Science and Technology(JST),and the Japan Society for the Promotion of Science(JSPS)KAKENHI(Grants-in-Aid for Scientific Research(A)19H00900 and Innovative Areas JP 18K19092 to T.0.).
Phosphatidylinositol(3,4,5)-triphosphate(PIP3),acting as a fundamental second messenger,is emerging as a promising biomarker for disease diagnosis and prognosis.However,the real time analysis of phosphoinositide in li...
关键词：Protein-protein interactions Protein engineering Fluorescent probes Optogenetic control Phosphatidylinosito (3 4 5)-triphosphate 
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