PTX

作品数：130被引量：286H指数：8
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相关作者：张凌姚力赵望泓张烜陈璇更多>>
相关机构：中日友好医院南方医科大学郑州大学北京大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划南方医科大学南方医院院长基金山西省青年科技研究基金更多>>
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Cathepsin B-responsive and gadolinium-labeled branched glycopolymer-PTX conjugate-derived nanotheranostics for cancer treatment被引量：4
《Acta Pharmaceutica Sinica B》2021年第2期544-559,共16页Hao Cai Yufan Xiang Yujun Zeng Zhiqian Li Xiuli Zheng Qiang Luo Hongyan Zhu Qiyong Gong Zhongwei Gu Yanhui Liu Hu Zhang Kui Luo 
financially supported by the National Natural Science Foundation of China(Nos.51873120,51673127,and 81621003);Department of Science and Technology of Sichuan Province(Nos.2018JY0574,2017SZ0006,18GJHZ0139,and 2018HH0006,China);1·3·5 Research Funds in West China Hospital of Sichuan University(ZYGD18028,China)
Multi-modal therapeutics are emerging for simultaneous diagnosis and treatment of cancer.Polymeric carriers are often employed for loading multiple drugs due to their versatility and controlled release of these drugs ...
关键词：STIMULI-RESPONSIVE Drug delivery Branched glycopolymers Biodegradability Nanomedicine THERANOSTICS 
Hyaluronic acid derivative-modified nano-structured lipid carrier for cancer targeting and therapy被引量：4
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2020年第7期571-580,共10页Xiao LIU Hai LIU Su-lan WANG Jing-wen LIU 
Project supported by the Zhejiang Provincial Natural Science Foundation of China(No.LY14H160016)。
To reduce the problems of poor solubility,high in vivo dosage requirement,and weak targeting ability of paclitaxel(PTX),a hyaluronic acid-octadecylamine(HA-ODA)-modified nano-structured lipid carrier(HA-NLC)was constr...
关键词：Paclitaxel(PTX) Hyaluronic acid-octadecylamine(HA-ODA) Nano-structured lipid carrier(NLC) Tumor targeting In vivo distribution 
Integration of phospholipid-drug complex into self-nanoemulsifying drug delivery system to facilitate oral delivery of paclitaxel被引量：1
《Asian Journal of Pharmaceutical Sciences》2019年第5期552-558,共7页Dawei Ding Bingjun Sun Weiping Cui Qin Chen Xuanbo Zhang Haotian Zhang Zhonggui He Jin Sun Cong Luo 
financially supported by the National Nature Science Foundation of China (No. 81703451);the China Postdoctoral Science Foundation (No. 2017M611269 and 2018T110233)
Self-nanoemulsifying drug delivery system(SNEDDS) has emerged as a promising platform to improve oral absorption of drugs with poor solubility and low permeability. However,large polarity molecules with insufficient l...
关键词：PTX PLDC SNEDDS PLDC-SNEDDS ORAL delivery 
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