QUORUM_SENSING

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Metabolic activities of marine ammonia-oxidizing archaea orchestrated by quorum sensing
《mLife》2024年第3期417-429,共13页Olivier Pereira Wei Qin Pierre E.Galand Didier Debroas Raphael Lami Corentin Hochart Yangkai Zhou Jin Zhou Chuanlun Zhang 
This work was supported by the National Natural Science Foundation of China(Nos.42321004 and 92351301);the Stable Support Plan Program of Shenzhen Natural Science Fund(20200925173954005);the Shenzhen Municipal Commission of Science and Technology Innovation(KCXFZ20211020174803005);the Guangdong Basic and Applied Basic Research Foundation(2021B 1515120080 and 2020B1515120012);the Shenzhen Key Laboratory of Marine Archaea Geo-Omics,Southern University of Science and Technology(ZDSYS201802081843490);the Agence Nationale de la Recherche(ANR)through the projects EUREKA(ANR-14-CE02-0004-01).
Ammonia-oxidizing archaea(AOA)play crucial roles in marine carbon and nitrogen cycles by fixing inorganic carbon and performing the initial step of nitrification.Evaluation of carbon and nitrogen metabolism popularly ...
关键词：AOA functional genes marine ammonia-oxidizing archaea NETWORKING quorum sensing Tara Oceans 
The phytopathogen Xanthomonas campestris senses and effluxes salicylic acid via a sensor HepR and an RND family efflux pump to promote virulence in host plants
《mLife》2024年第3期430-444,共15页Kai Song Ruifang Li Ying Cui Bo Chen Lian Zhou Wenying Han Bo-Le Jiang Ya-Wen He 
This work was financially supported by research grants from the National Natural Science Foundation of China(Nos.31972231 and 32172355 to H.Y.W.).
Salicylic acid(SA)plays an essential role in plant defense against biotrophic and semi-biotrophic pathogens.Following pathogen recognition,SA biosynthesis dramatically increases at the infection site of the host plant...
关键词：EFFLUX quorum sensing salicylic acid SENSOR Xanthomonas campestris 
Discovery of β-nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition and antivirulence factor therapeutics against Serratia marcescens
《mLife》2024年第3期445-458,共14页Jiang Wang Jingyi Yang Pradeepraj Durairaj Wei Wang Dongyan Wei Shi Tang Haiqing Liu Dayong Wang Ai-Qun Jia 
This work was supported by the National Natural Science Foundation of China(Nos.82160664 and 31760246);the Hainan Province Science and Technology Special Fund(ZDYF2024SHFZ103);the Natural Science Foundation of Hainan Province(222RC557 and 221QN170);Anhui Laboratory of Molecule-Based Materials(fzj21006).
Quorum sensing(Qs)inhibition has emerged as a promising target for directed drug design,providing an appealing strategy for developing antimicrobials,particularly against infections caused by drug-resistant pathogens....
关键词：biofilms quorum sensing Serratia marcescens virulence factors (E)-1-methyl-4-(2-nitrovinyl)benzene 
RsaL is a self-regulatory switch that controls alternative biosynthesis of two AHL-type quorum sensing signals in Pseudomonas aeruginosa PA1201
《mLife》2024年第1期74-86,共13页Ya-Wen He Zi-Jing Jin Ying Cui Kai Song Bo Chen Lian Zhou 
financially supported by grants from the National Key R&D Program of China(2018YFA0901900 to H.Y.W.);the National Natural Science Foundation of China(No.31972231 to H.Y.W)。
Pseudomonas aeruginosa is a ubiquitous and metabolically versatile microorganism naturally found in soil and water.It is also an opportunistic pathogen in plants,insects,animals,and humans.In response to increasing ce...
关键词：N-3-oxo-dodecanoyl homoserine lactone N-butanoyl-homoserine lactone Pseudomonas aeruginosa quorum sensing RsaL 
Dual functions:A coumarin–chalcone conjugate inhibits cyclic-di-GMP and quorum-sensing signaling to reduce biofilm formation and virulence of pathogens被引量：2
《mLife》2023年第3期283-294,共12页Yu Zhang Pramod Bhasme Dinesh S.Reddy Dejian Liu Zhaoxiao Yu Tianhu Zhao Yaqian Zheng Amit Kumar Haiying Yu Luyan Z.Ma 
the National Natural Science Foundation of China(91951204,32200149);the National Key R&D Program of China(2021YFA0909500,2021YFC2301004,2019YFC804104),and the CAS‐TWAS PhD Fellowship for Pramod Bhasme.
Antibiotic resistance or tolerance of pathogens is one of the most serious global public health threats.Bacteria in biofilms show extreme tolerance to almost all antibiotic classes.Thus,use of antibiofilm drugs withou...
关键词：biofilm cyclic-di-GMP exopolysaccharide Psl Pseudomonas aeruginosa quorum sensing 
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