Background Boanmycin hydrochloride, a new antitumor agent, has a short half-life and fast clearance speed in vivo. The aim of this research was to investigate the effectiveness of peritumor injection of boanmycin hydr...
Objective: The inhibitory action of fMLP-boanmycin (BAM) combination on the growth of mouse colon carcinoma and its action mechanisms were observed in order to provide experimental proof for probing novel regimen o...
从boanmycin产生菌轮枝链霉菌平阳变种(Streptomyces verticillus var. pingyangensis n. sp.)发酵产物中分离、纯化boanmycin相关物质A601。对A601进行光谱分析鉴定其化学结构,结果证实A601的化学结构为博来霉素B6,并对其碳谱进行了归属。
This work was supported by the "973" Major State Basic Research Project of china (No. G1998051104)
Objective: Chemotactic peptide may interfere with the process of tumor growth, invasion and metastasis by activating and attracting leukocytes containing macrophages. fMLP (CHO-Met-II e-Phe) is one of the chemotactic ...
Supported by the National Natural Science Foundation of China, No. 93090012-03
INTRODUCTIONBoanmycin (Bleomycin A6, BAM ), a newantitumor antibiotic, was isolated from manycomponents of bleomycin (BLM) produced bystreptomyces pingyangensis which were obtainedfrom a soil sample collected in Pingy...
Boanmycin (bleomycin A6 . BM) . an antitumor antibiotic, was conjugated to monoclonal antibodies including R19, H 111 and CCT2. The immunoconjugates exhibited selective cytotoxicity to related target cells including c...