supported by the National Key Research and Development Program of China(2020YFA0908300);the National Natural Science Foundation of China(32222069,32172349);the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(32021005);the Natural Science Foundation of Jiangsu Province(BK20202002).
Strengthening the expression level of integrated genes on the genome is crucial for consistently expressing key enzymes in microbial cell factories for efficient bioproduction in synthetic biology.In comparison to pla...
supported by the National Key Research and Development Program of China(2019YFA0905000);the National Natural Science Foundation of China(21871085 and 31971380);the Fundamental Research Funds for the Central Universities(222201714026).
Taxadiene is an important precursor for the biosynthesis of highly effective anticancer drug paclitaxel,but its microbial biosynthesis yield is very low.In this study,we employed Yarrowia lipolytica as a microbial hos...