This work was supported by the grants from the National Basic Research Program of China (No. 2005CB522400), National Natural Science Foundation of China (Nos. 90919044, 30971297, 81000221 and 81170518), Capital Medical Development Scientific Research Fund (No. 2007-2040), National Public Health Grand Research Foundation (No. 201202017) and The Capital of the Public Health Project (No. Z 111107067311070). Conflict of interest: none.
Background Cancer testis antigens (CTAs) are a novel group of tumor associated antigens.Demethylating agent decitabine was reported to be able to up-regulate CTAs through its hypomethylation mechanism,thus enhance t...