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DENDRITIC_CELLS: 作品数：431被引量：1944H指数：21; 导出分析报告; 相关作者：王胜军林玮许化溪刘恭植季晓辉更多>>; 相关机构：浙江大学医学院附属第二医院镇江医学院南京医科大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金中国博士后科学基金更多>>

Elucidating the synergistic roles of CD4^(+)T and dendritic cells in antitumor immunity: 《Cancer Biology & Medicine》2025年第1期1-5,共5页Xiubao Ren; A recent publication by Espinosa-Carrasco et al.1has illuminated the critical roles of intratumoral immune triads-a unique cluster of CD4^(+)T cells,CD8^(+)T cells,and dendritic cells(DCs)-in mediating effective antit...; 关键词：IMMUNITY TUMOR

The implication of dendritic cells in lung diseases:Immunological role of toll-like receptor 4: 《Genes & Diseases》2024年第6期258-272,共15页Shurui Xuan Yuan Ma Honglei Zhou Shengwei Gu Xin Yao Xiaoning Zeng; supported by the National Natural Science Foundation of China,China (No.81970016,81870039).; The immune responses play a profound role in the progression of lung lesions in both infectious and non-infectious diseases.Dendritic cells,as the"frontline"immune cells responsible for antigen presentation,set up a b...; 关键词：Dendritic cells IMMUNITY Lung diseases Pathogen recognition receptors Toll-like receptors 4

STING-activating dendritic cell-targeted nanovaccines that evoke potent antigen cross-presentation for cancer immunotherapy被引量：1: 《Bioactive Materials》2024年第12期345-365,共21页Nguyen Thi Nguyen Xuan Thien Le Woo Tak Lee Yong Taik Lim Kyung Taek Oh Eun Seong Lee Han-Gon Choi Yu Seok Youn; supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT,No.RS-2024-00352440 and No.NRF-2019R1A5A2027340).; Recently,nanovaccine-based immunotherapy has been robustly investigated due to its potential in governing the immune response and generating long-term protective immunity.However,the presentation of a tumor peptide-ma...; 关键词：DC-based nanovaccines Artificial antigen-presenting cells Type 1 conventional dendritic cells STING pathway activation Antigen cross-presentation

Cell membrane-coated mRNA nanoparticles for enhanced delivery to dendritic cells and immunotherapy: 《Asian Journal of Pharmaceutical Sciences》2024年第6期123-137,共15页Qiaoyun Li Junho Byun Dongyoon Kim Yina Wu Jaiwoo Lee Yu-Kyoung Oh; funded by grants from the National Research Foundation (NRF) of Korea,Ministry of Science and ICT,Republic of Korea (NRF-2021R1A2B5B03002123;NRF-2018R1A5A2024425;NRF-2022M3E5F1017919);the Alchemist Project of the Korea Evaluation Institute of Industrial Technology (KEIT 20018560,NTIS 1415184668); Cationic polymers such as polyethylenimine have been considered promising carriers for mRNA vaccines.However,their application is hindered by their inherent toxicity and a lack of targeted delivery capability.These is...; 关键词：Cell membrane coating Dendritic cells mRNA delivery Immune response Antitumor effect

Impact of nanoparticles on immune cells and their potential applications in cancer immunotherapy: 《BIOCELL》2024年第11期1579-1602,共24页JYOTHI B.NAIR ANU MARY JOSEPH SANOOP P MANU M.JOSEPH; Nanoparticles represent a heterogeneous collection of materials,whether natural or synthetic,with dimensions aligning in the nanoscale.Because of their intense manifestation with the immune system,they can be harveste...; 关键词：NANOTECHNOLOGY MACROPHAGES Dendritic cells Antigen presentation T lymphocytes

Tug of war:Understanding the dynamic interplay of tumor biomechanical environment on dendritic cell function: 《Mechanobiology in Medicine》2024年第3期7-21,共15页Brian Chesney Quartey Gabriella Torres Mei ElGindi Aseel Alatoom Jiranuwat Sapudom Jeremy C.M Teo; support from New York University Abu Dhabi(NYUAD)Faculty Research.Fund(AD266)。; Dendritic cells(DCs)play a pivotal role in bridging the innate and adaptive immune systems.From their immature state,scavenging tissue for foreign antigens to uptake,then maturation,to their trafficking to lymph nodes...; 关键词：Dendritic cells MECHANOBIOLOGY Biomechanical cues Antigen uptake Antigen presentation Immunotherapy

The current role of dendritic cells in the progression and treatment of colorectal cancer: 《Cancer Biology & Medicine》2024年第9期769-783,共15页Yuanci Zhang Songtao Ji Ge Miao Shuya Du Haojia Wang Xiaohua Yang Ang Li Yuanyuan Lu Xin Wang Xiaodi Zhao; This study was supported by grants from the National Natural Science Foundation of China(Grant Nos.82222058,82073197,82273142,and 82173256).; Colorectal cancer(CRC)is the third most common cancer and the second leading cause of cancer-related deaths worldwide.Dendritic cells(DCs)constitute a heterogeneous group of antigen-presenting cells that are important...; 关键词：Colorectal cancer dendritic cells tumor progression treatment strategies

Dysfunction of dendritic cells in tumor microenvironment and immunotherapy: 《Cancer Communications》2024年第9期1047-1070,共24页Jie Chen Yuhang Duan Junye Che Jianwei Zhu; National Natural Science Foundation of China,Grant/Award Numbers:81773621,82073751;National Science and Technology Major Project,Grant/Award Number:2019ZX09732001-019。; Dendritic cells(DCs)comprise diverse cell populations that play critical roles in antigen presentation and triggering immune responses in the body.However,several factors impair the immune function of DCs and may prom...; 关键词：DCs immunotherapy dendritic cells dysfunction of DCs tumor microenvironment

Tumor-derived DEFB1 induces immune tolerance by inhibiting maturation of dendritic cell and impairing CD8+T cell function in esophageal squamous cell carcinoma: 《Chinese Journal of Cancer Research》2024年第4期351-367,共17页Jingjing Duan Haotian Wang Minglu Liu Yin Chen Ning Li Jieqiong Liu Lingxiong Wang Lin Li Yaru Liu Pengfei Dong Xiuxuan Wang Zhongyi Fan Shunchang Jiao; supported by the National Natural Science Foundation of China(No.81972681,82103677);Tianjin Education Commission Research Plan Project(No.2021KJ201);Shenzhen High-level Hospital Construction Fund(No.G2022139);Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-009A).; Objective:CD8+T cells are the key effector cells in the anti-tumor immune response.The mechanism underlying the infiltration of CD8+T cells in esophageal squamous cell carcinoma(ESCC)has not been clearly elucidated.Me...; 关键词：CD8+T cells DEFB1 dendritic cells esophageal squamous cell carcinoma tumor immune microenvironment

3D Collagen Gels:A Promising Platform for Dendritic Cell Culture in Biomaterials Research: 《Proceedings of Anticancer Research》2024年第4期124-134,共11页Kirubanandan Shanmugam; The three-dimensional(3D)cell culture system has garnered significant attention in recent years as a means of studying cell behavior and tissue development,as opposed to traditional two-dimensional cultures.These syst...; 关键词：Three-dimensional cell culture Dendritic cells Type 1 collagen gels Bovine tendons and rat tails

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