supported by grants from National Natural Science Foundation of China (No. 81160249, 81301886 and 81760525);Science Foundation of Peking University Cancer Hospital (No. 2017 Zizhu-1);Open Project funded by Key Laboratory of Carcinogenesis and Translational Research;Ministry of Education/Beijing (2017 Open Project-3);Beijing Municipal Science & Technology Commission (No. Z171100001017136);Beijing Natural Science Foundation (No. 7171001);West China First-Class Discipline Construction Project in Basic Medicine funded by Ningxia Medical University
Objective: This study aimed to comprehensively assess Epstein-Barr virus(EBV)-induced methylation alterations of B cell across whole genome.Methods: We compared DNA methylation patterns of primary B cells and corr...
This work was supported by a grant from The National Natural Science Foundation of China (No.39730900-II).
Objective: To investigate the effects of Epstein- Barr virus (EBV) encoded latent membrane protein 1 (LMP1) expression on tumor cell differentiation in early-stage nasopharyngeal carcinoma (NPC). Methods: Thirty-one b...
supported by grants from the National Natural Science Foundation of China(No.39730200-Ⅱ);the National"ten-five"Key Project of China(No.2001BA703B07);the Department of Public Health;Guangdong Province(No.1998218).
Objective: To evaluate the value of combined assays of serum EBNA1-IgA and EA-IgG for serological diagnosis of nasopharyngeal carcinoma (NPC). Methods: The serum EBNA1-IgA and EA-IgG were tested by use of ELISA for 56...
supported by National Natural Science Foundation of China(No.30000087);"973"National Key Basic Research Program of China(No.G1998051201);the National Scientific Research Foundation for Excellent Young Scientist of China(No.39525022)
Objective: Tea polyphenols present in green tea show cancer chemopreventive effects in many tumor models. Epidemiological studies have also suggested that green tea consumption might be effective in the prevention of ...
The infections of human papilloma virus (HPV),herpes simplex virus type 2 (HSV-2) and Epstein-Barr virus (EBV) to human cervical epithelium are universal and some of them are associated with the development of cervica...
This report characterizes the J6-1 cell line derived from a Chinese acute myelomonocytic leukemia patient and previously reported to be associated with EBV. These studies showed that J6-1 cells were also infected with...
Epstein-Barr virus was considered as a caustive agent for Burrkitt' s lymphoma and non-malignant B lymphocytes proliferation. The recent studies revealed the striking association of the Infection of EBV with the devel...
The Epstein-Barr virus membrane antigen was constructed and inserted into vaccinia virus, Tian-tan strain in order to study the effect of this virus on EB infection and tumorogenesis. The EBV-derived membrane antigen ...