AIM To evaluate the importance of endoscopic ultrasonography(EUS) for small(≤ 10 mm) rectal neuroendocrine tumor(NET) treatment.METHODS Patients in whom rectal NETs were diagnosed by endoscopic resection(ER) at the P...
Supported by the National Natural Science Foundation of China,No.81260455 and No.81160065
AIM To investigate the role of the complement 5a(C5a)/C5 a receptor(C5a R) pathway in the pathogenesis of acute liver failure(ALF) in a mouse model.METHODS BALB/c mice were randomly assigned to different groups, and i...
Supported by National Natural Science Foundation of China,No.81272735;Class A Medical and Health Technology Program Project from Zhejiang Province,No.2010KY178;the Science and Technology Department of Hunan Province,No.2010Ck3013
AIM:To determine the role of NOB1,a regulator of cell survival in yeast,in human colorectal cancer cells.METHODS:Lentivirus-mediated small interfering RNA(si RNA) was used to inhibit NOB1 expression in RKO human color...
Supported by The Science and Technology Development Project of Guangdong Province,No.2011B031800240 and No.2012B031800389
Histopathological results are critical for the diagnosis and surgical decision regarding gastric cancer. How-ever, opposite opinions from radiology and pathology can sometimes affect clinical decisions. The two cases ...
Supported by Ministry of Sciences and Higher Education Grant ST-41 and ST-43
AIM:To investigate the influence of chronic pancreatitis(CP) on serum concentrations of amino acids.METHODS:Thirty-five male patients with alcoholic CP and 21 healthy male subjects were examined.Serum concentrations o...
Acute pancreatitis(AP) is an inflammatory condition of the pancreas caused by an imbalance in factors involved in maintaining cellular homeostasis.Earliest events in AP occur within acinar cells accompanied by other p...
AIM: To investigate whether peroxisome proliferatoractivated receptor γ (PPAR-γ) is expressed in human gastric carcinoma and whether PPAR-γ, is a potential target for gastric carcinoma therapy. METHODS: PPAR-γ...
Hepatitis B virus (HBV) infection is a global public health problem that concerns 350 million people worldwide. Individuals with chronic hepatitis B (CriB) are at increased risk of developing liver cirrhosis, hepa...
The Korea Research Foundation Grant funded by the Korean Government (MOEHRD, Basic Research Promotion Fund), KRF-2007-412-J00303;Ulsan University Hospital Biomedical Research Center Promotion Fund (UUH-2007-05)
AIM: To establish the role of FHIT in the pathogenesis hepatocellular carcinoma (HCC). METHODS: We examined genomic alterations, as well as, mRNA and protein expression patterns from the FHIT gene, in 48 surgically re...
Supported by a grant from the Korean Ministry of Science and Technology (Korean Systems Biology Research Grant, M1-0309-06-0002) partly by the research grant from Hallym University, Korea Co-first-authors: Kyu-Jin Park
AIM: We have previously demonstrated that hepatitis C virus (HCV) core protein is efficiently released into the culture medium in insect cells. The objective of this study is to characterize the HCV core secretion in ...