supported by the National Key Technology R&D Program of China(Grant Nos.2017YFA0103504 to XC,2018ZX10301402 to JRY);the National Natural Science Foundation of China(Grant Nos.31671320,31871320,and 81830103 to JRY);the start-up grants from the“100 Top Talents Program”of Sun Yat-sen University,China(Grant Nos.50000-18821112 to XC,50000-18821117 to JRY).
The secondary structure is a fundamental feature of both non-coding RNAs(ncRNAs)and messenger RNAs(mRNAs).However,our understanding of the secondary structures of mRNAs,especially those of the coding regions,remains e...