supported financially by the National Key R&D Program of China(grant no.2016YFA0501700);National Natural Science Foundation of China(grant nos.21433004,31700646,and 21933010),and NYU Global Seed Grant.
Threofuranosyl nucleic acid(TNA)is an analogue of DNA with a shift in the internucleotide linkages from the wild-type 5’-to-3’direction to 3’-to-2.’This alteration leads to higher chemical stability,less reactive ...