The work was supported by the National Natural Science Foundation of China(No.81200981,81,371,407);the Innovation Program of Shanghai Municipal Education Commission(No.13YZ026);the Intramural Program of the National Institute of Neurological Disorders and Stroke.
Photophobia is a common symptom seen in many neurologic disorders,however,its pathophysiology remains unclear.Even the term is ambiguous.In this paper,we review the epidemiology and clinical manifestations of photopho...
Expert introduction Dr.Russell Foster(Figure 1)is the professor of Nuffield Laboratory of Ophthalmology,Head of the Nuffield Laboratory of Ophthalmology and the Sleep and Circadian Neuroscience Institute.Prior to this...
supported by the Spanish Ministry of Education and Science SAF2015-67643-P;Spanish Ministry of Economy and Competitiveness ISCIII-FEDER “Una manera de hacer Europa” PI13/00643
Light is an electromagnetic stimulus that in mammals is sensed by specialized neurons in the retina.The physiological response to light encompasses two fundamental and different functional outputs:image-forming and n...
Supported by the Chongqing Internationa Cooperation Key Projects(No.CSTC2013GJHZ10004);National Basic Research Program of China(973 Program No.2013CB967002)
AIM: To explore whether ectopic expression of human melanopsin can effectively and safely restore visual function in rd1 mice.· METHODS: Hematoxylin-eosin staining of retinal sections from rd1 mice was used to dete...
supported by the National Basic Research Program of China (2009CB320900 to Pu MingLiang,2011CB510206 to Pu MingLiangand Gao Jie);National Natural Science Foundation of China(30831160516 to Pu MingLiang);NIH EY04067 (N.C. Brecha);VAMerit Review (N.C. Brecha).;supported by a summer fellowship from the PKU-UCLA Joint Research Institute
In this study, the role of melanopsin-expressing retinal ganglion cells (mRGCs) in the glaucoma-induced depressive behavioral response pattern was investigated. The CFP-D2 transgenic glaucoma animal model from five ...
supported by grants from the National Institutes of Health, the National Institute of Neurological Disorders and Stroke R01 NS035615;the National Eye Institute R01 EY017809
A new mammalian photoreceptor was recently discovered to reside in the ganglion cell layer of the inner retina.These intrinsically photosensitive retinal ganglion cells(ipRGCs) express a photopigment,melanopsin,that c...