supported financially by National Natural Science Foundation of China(21002098,20932007);‘western light’ Research Program from Chinese Academy of Sciences(Y1C1011);National New Drug Innovation Major Project of China(2011ZX09307-002-02)
supported by Innovative Program of the Chinese Academy of Sciences(KSCX2-YW-G-06-03);the West Light Fund of Chinese Academy of Sciences(09C102);the Key Research Projects of Chengdu Bureau of Science and Technology(07GGYB214SW)