enantiomer being preferentially cleared into the urine.To study the stereoselectivity in renal clearance of trans-tramadol and its active metabolite, trans-O-demethyltramadol. METHODS: The right kidneys were isolated ...
AIM: To study the stereoselectivity in pharmacokinetics of the enantiomers of trans- tramadol (trans- T) and its active metabolite, frans-O-demethyltramadol (MI) in human subjects. METHODS: Trans-T hydrochloride susta...