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Effects ofβ_2-Adrenergic Antagonist on Cytosolic Ca^(2+) in Ventricular Myocytes from Infarcted Rat Heart被引量：2
《South China Journal of Cardiology》2006年第1期10-13,共4页杨蕙 伍卫 曾冲 邓春玉 方昶 陈珊茗 
Objectives To investigate the effects of β2-adrenergic antagonist on cytosolic Ca^2 ＋ （[Ca^2＋ ]i） in ventricular myocytes from infarcted rat heart. Methods A ligature was placed around left anterior descending co...
关键词：Myocardial infarction Beta2-adrenergic receptor Ventricular myocyte Cytosolic Ca^2＋ 
Cytosolic phospholipase A2α modulates cell-matrix adhesion via the FAK/paxillin pathway in hepatocellular carcinoma被引量：2
《Cancer Biology & Medicine》2019年第2期377-390,共14页Piao Guo Yuchao He Lu Chen Lisha Qi Dongming Liu Ziye Chen Manyu Xiao Liwei Chen Yi Luo Ning Zhang Hua Guo 
supported by grants from Key Project of Tianjin Natural Science Foundation (Grant No.18JCZDJC35200);NSFC-FRQS program (Grant No.81661128009);The Science & Technology Development Fund of Tianjin Education Commission for Higher Education (Grant No.2017KJ202);Scientific Research Foundation for Returned Scholars and Doctoral Program of Tianjin Medical University Cancer Institute and Hospital (Grant No.B1703)
Objective: To explore the effect of cytosolic phospholipase A2α(cPLA2α) on hepatocellular carcinoma(HCC) cell adhesion and the underlying mechanisms.Methods: Cell adhesion, detachment, and hanging-drop assays were u...
关键词：HEPATOCELLULAR carcinoma CYTOSOLIC PHOSPHOLIPASE A2α cell-matrix adhesion FAK PAXILLIN 
Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage被引量：3
《Neuroscience Bulletin》2010年第1期8-16,共9页孙中伟 张蓝 竺淑佳 陈温纯 梅兵 
supported by thegrants from National Natural Science Foundation of China(No. 30870790);Shanghai Science and Technology Commis-sion (No. 06DZ19003);in part by National Basic ResearchDevelopment Program (973) of China (No. 2009CB918402)
Objective To investigate the mechanisms of excitotoxic effects of glutamate on human neuroblastoma SH-SY5Y cells. Methods SH-SY5Y cell viability was measured by MTT assay. Other damaged profile was detected by lactate...
关键词：GLUTAMATE EXCITOTOXICITY cytosolic calcium oxidative damage 
Mutation of the Arabidopsis Calmodulin-Like Protein CML37 Deregulates the Jasmonate Pathway and Enhances Susceptibility to Herbivory被引量：12
《Molecular Plant》2014年第12期1712-1726,共15页Sandra S. Scholz Jyothilakshmi Vadassery Monika Heyer Michael Reichelt Kyle W. Bender Wayne A. Snedden Wilhelm Boland Axel Mithofer 
Throughout their life, plants are challenged by various abiotic and biotic stress factors. Among those are attacks from herbivorous insects. The molecular mechanisms underlying the detection of herbivores and the subs...
关键词：HERBIVORY oral secretion JASMONATES cytosolic calcium calmodulin-like proteins. 
Research Article Dynamically crosslinked nanocapsules for the efficient and serumresistant cytosolic protein delivery
《Nano Research》2024年第3期1760-1771,共12页Qiang Yang Ningyu Liu Ziyin Zhao Xun Liu Lichen Yin 
supported by the Natural Science Foundation of Jiangsu Province(No.BK20220245);the National Natural Science Foundation of China(Nos.52273144 and 82241008);Collaborative Innovation Center of Suzhou Nano Science&Technology,the 111 project,Suzhou Key Laboratory of Nanotechnology and Biomedicine,and Joint International Research Laboratory of Carbon-Based Functional Materials and Devices.
Intracellular protein delivery is critical to the development of protein-based biopharmaceuticals and therapies.However,current delivery vectors often suffer from complicated syntheses,low generality among various pro...
关键词：NANOCAPSULES dynamic crosslinking cytosolic protein delivery serum resistance antitumor therapy genome editing 
Damaging Effect of Cigarette Smoke Extract on PrimaryCultured Human Umbilical Vein Endothelial Cells and Its Mechanism被引量：4
《Biomedical and Environmental Sciences》2004年第2期121-134,共14页Yu-MEIYANG GENG-TAOLIU 
Objective To investigate the cellular effects of cigarette smoke extract (CSE) on primarily cultured human umbilical vein endothelial cells (HUVEC). Methods The effects of CSE (5%-20%) and nicotine (10-4 mol/L) on HUV...
关键词：Cigarette smoke extracts (CSE) Human umbilical endothelial cell (HUVEC) VIABILITY Proliferation ANGIOGENESIS Mitochondrial membrane potential Cytosolic calcium Bcl-2 BCL-2/BAX p53 
Real-time Assessment of Cytosolic, Mitochondrial, and Nuclear Calcium Levels Change in Rat Pheochromocytoma Cells during Pulsed Microwave Exposure Using a Genetically Encoded Calcium Indicator被引量：3
《Biomedical and Environmental Sciences》2017年第12期927-931,共5页HU Shao Hua WANG Hui LU Li ZHOU Hong Mei WANG Chang Zhen GAO Ya Bing DONG Ji PENG Rui Yun 
supported by the National Natural Science Foundation of China[No.31400716 and No.61401497]
Little information is available about the effects of exposure to pulsed microwaves on neuronal Ca^2＋ signaling under non-thermal conditions. In this study, rat pheochromocytoma （PC12） cells were exposed to pulsed m...
关键词：Real-time Assessment of Cytosolic MITOCHONDRIAL Nuclear Calcium Levels 
Involvement of Polyamine Oxidase in Abscisic Acidinduced Cytosolic Antioxidant Defense in Leaves of Maize被引量：3
《Journal of Integrative Plant Biology》2009年第3期225-234,共10页Beibei Xue Aying Zhang Mingyi Jiang 
Supported by the Science Foundation for New Teachers of Doctoral Subject Point of the Ministry of Education of China (20070307018).
Using pharmacological and biochemical approaches, the role of maize polyamine oxidase （MPAO） in abscisic acid （ABA）- induced antioxidant defense in leaves of maize （Zea mays L.） plants was investigated. Exogenou...
关键词：abscisic acid cytosolic antioxidant defense hydrogen peroxide polyamine oxidase Zea mays. 
Remarkable difference of phospholipid molecular chirality in regulating PrP aggregation and cell responses
《Chinese Chemical Letters》2023年第2期236-243,共8页Cunli Wang Xue Wang Dongdong Wang Shengxu Qian Fusheng Zhang Mingyang Li Minmin Li Wenqi Lu Bo Liu Guangyan Qing 
supported by the National Natural Science Foundation of China (Nos. 21775116 and 21922411);DICP Innovation Funding (Nos. DICP-RC201801 and DICP I202008);Liao Ning Revitalization Talents Program (No. XLYC1802109)。
Prion diseases are fatal neurodegenerative diseases that can cause severe dementia.The misfolding and accumulation of the prion peptide (PrP)_(106–126) is crucial,and this process is closely relevant to biological me...
关键词：Prion disease LIPOSOME CHIRALITY Interface Cytosolic Ca^(2+) 
白细胞介素-1β对人胶质细胞瘤细胞内环氧合酶-2系统的调节机制被引量：3
《中华医学杂志》2015年第9期697-700,共4页杨允学 刘飞 刘超 
目的 探讨白细胞介素（IL）-1β调节人胶质细胞瘤内环氧合酶（COX）-2系统表达的分子机制.方法 以2.5 μg/L IL-1 β刺激人胶质瘤细胞H4细胞,在刺激培养的12、24、48和72 h收集细胞及上清液.以不同浓度的p38和p42/44 MAPK信号抑制剂SB20...
关键词：神经胶质瘤 细胞系 白细胞介素-1Β 环氧化酶-2 磷脂酶A2 胞质型 
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