supported in part by the National Natural Science Foundation of China (Grant Nos. 31071166 and 81373085);Natural Science Foundation of Guangdong Province (Grant No. 8251008901000007);Science and Technology Planning Project of Guangdong Province (Grant No. 2009A030301004);Dongguan City Science and Technology Project (Grant No. 2011108101015);the Guangdong Medical College Funds (Grant Nos. JB1214, XG1001, XZ1105 and STIF201122)
Genetic studies are traditionally based on single-gene analysis. The use of these analyses can pose tremendous challenges for elucidating complicated genetic interplays involved in complex human diseases. Modern pathw...