体表神经刺激足三里在急性胰腺炎治疗中的应用研究  

Application Study on Superficial Nerve Stimulation of Zusanli in Treatment of Acute Pancreatitis

作　　者：周明明 吴京展[1] 蔡剑梅[1] 覃丽英 郭均娜 谭丽春 ZHOU Mingming;WU Jingzhan;CAI Jianmei;QIN Liying;GUO Junna;TAN Lichun(Gastroenterology Department,Guangxi Medical University The Second Affiliated Hospital,Nanning,Guangxi 530007)

机构地区：[1]广西医科大学第二附属医院消化内科,广西南宁530007

出　　处：《智慧健康》2023年第10期237-240,共4页Smart Healthcare

基　　金：广西壮族自治区中医药管理局项目《体表神经调控对急性胰腺炎腹痛的影响研究》(项目编号:GZZC2020185)

摘　　要：目的探讨体表神经刺激足三里在急性胰腺炎治疗中的临床应用价值。方法选择广西医科大学第二附属医院在2020年1月-2021年6月收治的急性胰腺炎患者108例为研究对象,按照随机数字法分为两组,各54例。对照组实施内科保守治疗,包括禁食、胃肠减压、质子泵抑制剂、生长抑素的使用和大黄灌肠、芒硝外敷等干预,治疗组联合应用胃肠多功能仪实施体表穴位神经刺激治疗,比较两组治疗后的舒适状况(GCQ评分)、干预过程中的机体热量摄入情况、干预后的肠道内毒素水平和肠道菌群定植入能力,统计两组并发症发生情况。结果治疗后,治疗组GCQ评分分项及总分高于对照组(P<0.05);干预后,治疗组和对照组热量摄入值分别为(125.7±26.3)kJ/(kg·d)和(114.7±23.5)kJ/(kg·d),均高于同组干预前(P<0.05);干预后,观察组肠道内毒素水平为(0.9±0.2)EU/mL低于对照组的(2.3±0.5)EU/mL(P<0.05);干预后,观察组出现脓毒血症、肺部感染、凝血功能障碍、电解质紊乱的总比例显著低于对照组(P<0.05)。结论针对急性胰腺炎患者,体表神经刺激足三里干预对缓解腹痛、提高患者舒适度、改善机体营养物质摄入、调节肠道菌群、减少治疗并发症有重要意义。Objective To explore clinical application value of superficial nerve stimulation of Zusanli in treatment of acute pancreatitis.Methods The paper chose 108 patients with acute pancreatitis admitted to Guangxi Medical University the Second Affiliated Hospital from January 2020 to June 2021 as study objects,and divided them into two groups according to random number method,with 54 cases in each group.Control group was treated with conservative internal medicine treatment,including fasting,gastrointestinal decompression,proton pump inhibitors,somatostatin,rhubarb enema,and external application of mirabilite,treatment group with superficial acupoint nerve stimulation treatment with gastrointestinal multifunctional instrument.Comfort status(GCQ scores),body heat intake during intervention process,intestinal endotoxin levels after intervention,and intestinal microbiota implantation ability were compared between two groups,incidence of complications was calculated between two groups.Results After treatment,sub and total GCQ scores of treatment group were higher than control group(P<0.05).After intervention,calorie intake values of treatment group and control group were(125.7±26.3)kJ/(kg•d)and(114.7±23.5)kJ/(kg•d)respectively,higher than before intervention in the same group(P<0.05).After intervention,intestinal endotoxin level in observation group was(0.9±0.2)EU/ml,lower than(2.3±0.5)EU/ml in control group,(P<0.05).After intervention,total proportion of sepsis,pulmonary infection,coagulation dysfunction,and electrolyte disorders in observation group was 3.7%,significantly lower than 29.6%in control group(P<0.05).Conclusion Superficial nerve stimulation at Zusanli intervention is of great significance in alleviating abdominal pain,improving patient comfort,body nutrient intake,regulating intestinal microbiota,and reducing treatment complications of acute pancreatitis patients.

关 键 词：足三里 体表神经刺激 急性胰腺炎 舒适度 胃肠道功能 肠道菌群 并发症 

分 类 号：R576[医药卫生—消化系统]