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医药卫生—消化系统: 作品数：343596被引量：558263H指数：179; 导出分析报告; 相关作者：李兆申范建高许国铭陆伦根侯晓华更多>>; 相关机构：第二军医大学华中科技大学复旦大学武汉大学更多>>; 发文主题：肝硬化疗效观察消化性溃疡溃疡性结肠炎幽门螺杆菌更多>>; 相关期刊：更多>>; 发文基金：国家自然科学基金国家科技重大专项国家重点基础研究发展计划广东省自然科学基金更多>>

Positive impact of indicaxanthin from Opuntia ficusindica fruit on high-fat diet–induced neuronal damage and gut microbiota dysbiosis: 《Neural Regeneration Research》2026年第1期324-332,共9页Simona Terzo Antonella Amato Pasquale Calvi Marta Giardina Domenico Nuzzo Pasquale Picone Antonio Palumbo-Piccionello Sara Amata Ilenia Concetta Giardina Alessandro Massaro Ignazio Restivo Alessandro Attanzio Luisa Tesoriere Mario Allegra Flavia Mulè; funding from the European Union -NextGenerationEU through the Italian Ministry of University and Research under PRIN PNRR REG D.R.1718-2022– Project number PRJ-1575 INDICA。; Indicaxanthin is a betalain that is abundant in Opuntia ficus-indica orange fruit and has antioxidative and anti-inflammatory effects. Nevertheless, very little is known about the neuroprotective potential of indicaxa...; 关键词：gut microbiota dysbiosis high-fat diet indicaxanthin MICROFLORA neuronal apoptosis NEURODEGENERATION NEUROINFLAMMATION obesity Opuntia ficus-indica fruit

NLRP3 inflammasome and gut microbiota–brain axis:A new perspective on white matter injury after intracerebral hemorrhage: 《Neural Regeneration Research》2026年第1期62-80,共19页Xiaoxi Cai Xinhong Cai Quanhua Xie Xueqi Xiao Tong Li Tian Zhou Haitao Sun; supported by the Guangdong Basic and Applied Basic Research Foundation,No.2023A1515030045(to HS);Presidential Foundation of Zhujiang Hospital of Southern Medical University,No.yzjj2022ms4(to HS)。; Intracerebral hemorrhage is the most dangerous subtype of stroke,characterized by high mortality and morbidity rates,and frequently leads to significant secondary white matter injury.In recent decades,studies have rev...; 关键词：gut microbiota gut microbiota–brain axis immune intracerebral hemorrhage NEUROINFLAMMATION NLRP3 protein stroke THERAPEUTICS white matter injury

Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease:lessons from animal studies: 《Neural Regeneration Research》2025年第12期3461-3475,共15页Wouter Claeys Anja Geerts Lien Van Hoecke Christophe Van Steenkiste Roosmarijn E.Vandenbroucke; supported by grants from the Research Foundation–Flanders(11A6420N,1268823N to WC and LVH);a FWO Junior Research Project Grant(G055121N to REV);VIB.AG is a senior clinical researcher of the Research Foundation–Flanders(1805718N)。; Hepatic encephalopathy,defined as neuropsychiatric dysfunction secondary to liver disease,is a frequent decompensating event in cirrhosis.Its clinical impact is highlighted by a notable increase in patient mortality r...; 关键词：AMMONIA ASTROCYTES CIRRHOSIS hepatic encephalopathy MICROGLIA NEUROINFLAMMATION osmotic stress oxidative stress systemic inflammation

Interaction between gut virome and microbiota on inflammatory bowel disease: 《World Journal of Methodology》2025年第3期17-21,共5页Xiao-Long Li Mueen Megdadi Humair S Quadri; Inflammatory bowel disease(IBD),encompassing Crohn's disease and ulcerative colitis,is a chronic condition marked by recurring gastrointestinal inflammation.While immune,genetic,and environmental factors are well-stud...; 关键词：Virome MICROBIOTA Inflammatory bowel disease LYSOGENY Horizontal gene transfer

Gut virome and its emerging role in inflammatory bowel disease: 《World Journal of Methodology》2025年第3期22-24,共3页Rahat Khatoon Khokhar Abdulqadir J Nashwan; Inflammatory bowel disease(IBD)is a progressive multifactorial inflammatory disease of the gut.The cause of IBD is yet unknown.Some researchers have shown that genetic factors,environmental factors,and the gut microbi...; 关键词：Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses

Comparison of standard vs auxiliary(contrast or elastography)endoscopic ultrasound-guided fine needle aspiration/biopsy in solid pancreatic lesions:A meta-analysis: 《World Journal of Methodology》2025年第3期196-208,共13页Mitali Madhumita Rath Prajna Anirvan Jijo Varghese Tara Prasad Tripathy Ranjan K Patel Manas Kumar Panigrahi Suprabhat Giri; BACKGROUND Endoscopic ultrasound-guided fine-needle aspiration/biopsy(EUS-FNA/B)is the most common modality for tissue acquisition from pancreatic masses.Despite high specificity,sensitivity remains less than 90%.Auxi...; 关键词：Endoscopic ultrasonography Fine-needle aspiration Biopsies Pancreatic ductal carcinomas Contrast media ELASTOGRAPHY

Third space endoscopy pulmonary complications and chylothorax post peroral endoscopic myotomy: 《World Journal of Methodology》2025年第3期70-79,共10页Ahmed Tawheed Alaa Ismail Ahmed El-Tawansy Karim Maurice Ahmed Ali Amr El-Fouly Ahmad Madkour; Third-space endoscopy(TSE)has emerged as an effective treatment modality for various gastrointestinal motility diseases and gastrointestinal tumors.TSE is based on the concept of working in the submucosa using a mucos...; 关键词：ENDOSCOPY Third-space endoscopy Submucosal endoscopy Per oral endoscopic myotomy Endoscopic submucosal dissection Pulmonary complications CHYLOTHORAX Pleural effusion

Machine learning-based models for prediction of in-hospital mortality in patients with dengue shock syndrome: 《World Journal of Methodology》2025年第3期89-99,共11页Luan Thanh Vo Thien Vu Thach Ngoc Pham Tung Huu Trinh Thanh Tat Nguyen; BACKGROUND Severe dengue children with critical complications have been attributed to high mortality rates,varying from approximately 1%to over 20%.To date,there is a lack of data on machine-learning-based algorithms ...; 关键词：Dengue shock syndrome Dengue mortality Machine learning Supervised models Logistic regression Random forest K-nearest neighbors Support vector machine Extreme Gradient Boost Shapley addictive explanations

重症急性胰腺炎伴腹内压升高患者经CRRT治疗的临床研究: 《黑龙江医药科学》2025年第4期150-151,155,共3页李雅婷王伟何清浩; 南阳市医学科技攻关计划项目,编号:2021-LH-0136。; 目的:探究重症急性胰腺炎(SAP)伴腹内压升高患者应用连续性肾脏替代治疗(CRRT)的临床效果和安全性。方法:选取2022年5月至2024年5月南阳市中心医院收治的78例SAP伴腹内压升高患者,采用随机信封法为A组(行常规治疗,n=39例)和B组(在A组的...; 关键词：重症急性胰腺炎腹内压连续性肾脏替代治疗疗效安全性

斑点追踪技术评价肝硬化心肌病患者左心功能的研究进展: 《河北北方学院学报(自然科学版)》2025年第8期62-66,共5页蔡道琴温德惠徐乐张力维; 2021年度河北省医学科学研究课题计划项目(No.20211139)。; 肝硬化心肌病(cirrhotic cardiomyopathy,CCM)是肝硬化并发症之一,静息状态下无异常,应激状态下可导致严重心力衰竭。对CCM患者早期准确的诊断和及时正确的干预治疗,有利于改善患者的长期预后。斑点追踪技术可以提供更准确的心肌应变信...; 关键词：肝硬化心肌病斑点追踪技术左心室整体纵向应变左房应变左心功能

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