CIRRHOSIS

作品数:1423被引量:7223H指数:35
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相关领域:医药卫生更多>>
相关作者:陆忠华于亚杰陈菊娣居朝霞周美芳更多>>
相关机构:中华医学会解放军第302医院香港大学复旦大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划北京市自然科学基金更多>>
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Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease:lessons from animal studies
《Neural Regeneration Research》2025年第12期3461-3475,共15页Wouter Claeys Anja Geerts Lien Van Hoecke Christophe Van Steenkiste Roosmarijn E.Vandenbroucke 
supported by grants from the Research Foundation–Flanders(11A6420N,1268823N to WC and LVH);a FWO Junior Research Project Grant(G055121N to REV);VIB.AG is a senior clinical researcher of the Research Foundation–Flanders(1805718N)。
Hepatic encephalopathy,defined as neuropsychiatric dysfunction secondary to liver disease,is a frequent decompensating event in cirrhosis.Its clinical impact is highlighted by a notable increase in patient mortality r...
关键词:AMMONIA ASTROCYTES CIRRHOSIS hepatic encephalopathy MICROGLIA NEUROINFLAMMATION osmotic stress oxidative stress systemic inflammation 
Cirrhosis after pancreaticoduodenectomy for pancreatic cancer
《Hepatobiliary & Pancreatic Diseases International》2025年第2期232-236,共5页Rui Su Hong-Na Liu Yu-Bo Wang Yun Bai 
To the Editor:Nonalcoholic fatty liver disease(NAFLD)is a clinicopathological syndrome characterized by excessive intracellular lipid accumulation in hepatocytes,not attributed to alcohol,viral infections,or other wel...
关键词:IMPAIRED NAFLD HEPATIC 
Incidence and efficacy of strategies for preventing hepatic encephalopathy following transjugular intrahepatic portosystemic shunt:A meta-analysis
《World Journal of Hepatology》2025年第4期120-136,共17页Xiao-Tong Xu Min-Jie Jiang Yun-Lai Fu Fang Xie Jian-Jun Li Qing-Hua Meng 
BACKGROUND Hepatic encephalopathy(HE)is a primary complication following transjugular intrahepatic portosystemic shunt(TIPS),but the utility of pharmacological prophylaxis for HE is unclear.AIM To assess the HE incide...
关键词:Transjugular intrahepatic portal shunt Hepatic encephalopathy CIRRHOSIS Prevention LACTULOSE RIFAXIMIN 
Management of hepatic encephalopathy following transjugular intrahepatic portosystemic shunts:Current strategies and future directions
《World Journal of Gastroenterology》2025年第15期8-23,共16页Ying Li Yu-Tong Wu Hao Wu 
Supported by the National Natural Science Foundation of China,No.82270649.
Transjugular intrahepatic portosystemic shunts(TIPSs)are generally used for the management of complications of portal hypertension in patients with decompensated cirrhosis.However,hepatic encephalopathy(HE),which impa...
关键词:CIRRHOSIS Portal hypertension Transjugular intrahepatic portosystemic shunt Hepatic encephalopathy Pathophysiological mechanisms Management strategies 
Predictive models and clinical manifestations of intrapulmonary vascular dilatation and hepatopulmonary syndrome in patients with cirrhosis:Prospective comparative study
《World Journal of Gastroenterology》2025年第15期60-78,共19页Zhi-Peng Wu Ying-Fei Wang Feng-Wei Shi Wen-Hui Cao Jie Sun Liu Yang Fang-Ping Ding Cai-Xia Hu Wei-Wei Kang Jing Han Rong-Hui Yang Qing-Kun Song Jia-Wei Jin Hong-Bo Shi Ying-Min Ma 
Supported by the National Key Research and Development Program of China,No.2022YFC2305002;Beijing Natural Science Foundation,No.7232079;Middle-aged and Young Talent Incubation Programs(Clinical Research)of Beijing Youan Hospital,No.BJYAYY-YN2022-12,No.BJYAYY-YN2022-13,and No.BJYAYY-YN2022-01;the China Postdoctoral Science Foundation,No.2023M732410 and No.2024T170595.
BACKGROUND Patients with cirrhosis with hepatopulmonary syndrome(HPS)have a poorer prognosis.The disease has a subtle onset,symptoms are easily masked,clinical attention is insufficient,and misdiagnosis rates are high...
关键词:Liver cirrhosis Hepatopulmonary syndrome Prediction model Clinical parameters Biomarkers 
Genetic intersection of human leukocyte antigen-DP/DQ and hepatitis B virus
《World Journal of Gastroenterology》2025年第16期101-103,共3页Jin-Wei Zhang 
Supported by National Natural Science Foundation of China,No.82170406 and No.81970238.
Hepatitis B virus infection remains a significant global health challenge,particularly in endemic regions like Vietnam.This article examines the groundbreaking study by Nguyen et al,which investigates the relationship...
关键词:Human leukocyte antigen Hepatitis B virus Hepatocellular carcinoma CIRRHOSIS Single nucleotide polymorphism Multi-clustering analysis VIETNAM 
Deadly intersection:Schistosomiasis,hepatopulmonary syndrome,and cirrhosis
《World Journal of Hepatology》2025年第4期7-10,共4页David Jerez Diaz Patrick Twohig 
In this editorial,we comment on the article by Rolim et al in World Journal of Hepatology,which highlights the impacts of hepatopulmonary syndrome(HPS)related to schistosomiasis in patients with and without cirrhosis....
关键词:SCHISTOSOMIASIS Portal hypertension Hepatopulmonary syndrome SURVIVAL MORTALITY Non-cirrhotic portal hypertension 
Rifaximin-αuse is associated with improved muscle mass in patients with cirrhosis
《World Journal of Hepatology》2025年第4期43-52,共10页Thomas Worland Penelope Hey Darren Wong Ross Apostolov Roseanne Kimberley Chan Marie Sinclair Paul Gow 
Supported by Norgine,the marketing authorization holder of rifaximin-α(Xifaxan©).
BACKGROUND Sarcopaenia is associated with a two-fold higher mortality rate in patients with cirrhosis independent of liver disease severity.Few treatments for cirrhosis related sarcopaenia exist beyond optimal nutriti...
关键词:RIFAXIMIN ENCEPHALOPATHY CIRRHOSIS Liver transplantation Sarcopaeni 
Hypochloremia is an underutilised prognostic marker in patients with advanced liver cirrhosis and liver failure
《World Journal of Hepatology》2025年第3期42-49,共8页Jinit R Soni Sudheer Marrapu Ramesh Kumar 
Patients with advanced liver cirrhosis and liver failure frequently experience abnormalities in their serum electrolyte levels.In such patients,hyponatremia has been identified as a predictor of poor outcomes.However,...
关键词:CHLORIDE Hypochloremia Liver failure CIRRHOSIS HYPONATREMIA PROGNOSIS 
Establish and validate an artificial neural networks model used for predicting portal vein thrombosis risk in hepatitis B-related cirrhosis patients
《World Journal of Hepatology》2025年第3期90-101,共12页Pei-Pei Meng Fei-Xiang Xiong Jia-Liang Chen Yang Zhou Xiao-Li Liu Xiao-Min Ji Yu-Yong Jiang Yi-Xin Hou 
Supported by The Beijing Hospitals Authority Youth Programme,No.QMl220201802.
BACKGROUND The portal vein thrombosis(PVT)can exacerbate portal hypertension and lead to complications,increasing the risk of mortality.AIM To evaluate the predictive capacity of artificial neural networks(ANNs)in qua...
关键词:Machine learning Portal vein thrombosis RISK Hepatitis B-related cirrhosis 
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