supported by research grants from the Michael J Fox Foundation for Parkinson’s Research(grant numbers:17244 and 023410);Science Foundation Ireland(Grant Numbers:19/FFP/6554)(to ED)。
Stem cell-based brain repair is a promising emergent therapy for Parkinson's disease based on years of foundational research using human fetal donors as a cell source.Unlike current therapeutic options for patients,th...
supported by the National Natural Science Foundation of China,No.81971177(to YK);the Natural Science Foundation of Beijing,No.7222198(to NH);the Peking University People's Hospital Research and Development Fund,No.RDX2021-01(to YK)。
FK506(Tacrolimus)is a systemic immunosuppressant approved by the U.S.Food and Drug Administration.FK506 has been shown to promote peripheral nerve regeneration,however,its precise mechanism of action and its pathways ...
supported by the National Natural Science Foundation of China(No.82373021);1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(No.ZYYC23010);the Natural Science Foundation of Science and Technology Department of Sichuan Province(No.2023ZYD0094);the National Clinical Research Center for Geriatrics(No.Z2021JC001).
Background:To date,no direct comparisons have been performed to compare the effectiveness of all epidermal growth factor receptor-tyrosine kinase inhibitors(EGFR-TKIs)against EGFR mutation-positive non-small cell lung...
supported by the Central Government Guiding Local Scientific and Technological Development Funds and Health Commission for Qinghai Province in China(No.2018-wjzdx-48).
Background:Breast cancer(BC)is the most diagnosed cancer worldwide,and patients'survival decreases with metastasis.We conducted a retrospective study using data derived from the Surveillance,Epidemiology,and End Resul...
Former Chicago Bear Steve McMichael was inducted into the Pro Football Hall of Fame.[However],this story is not that the,formidable defensive tackle was admitted to the Hall of Fame but that he survived to see it.
This series of films is the first documentary of its kind to present a few of the weirdest foods across China.Throughout human history,the foods that people rely on for survival have gradually become more appetizing,c...
supported by grants from the National Natural Science Foundation of China(No.32373115);the Earmarked Fund for Agriculture Seed Improvement Project of Shandong Province(Nos.2022LZGCQY010,2021ZLGX03 and 2021TSGC1240);the China Agriculture Research System Project(No.CARS-49)。
Crassostrea gigas is distinguished by its robust fertility,adaptability to various environmental conditions,and rich nutritional profile,which render it a cornerstone of the global shellfish market.Tetraploid oysters,...
BACKGROUND Renal cell carcinoma(RCC)is treated with surgical resection as the gold standard,as it is notoriously resistant to systemic therapy.Advancements with targeted therapies contribute to declining mortality,but...
Supported by Natural Science Foundation of Tianjin,No.21JCYBJC01140;Key Project of Tianjin Science and Technology Bureau Applied Basic Research,No.23JCZDJC01200;Key Project of Scientific Research Plan of Tianjin Municipal Education Commission,No.2023YXZD07;Project of Tianjin Science and Technology Bureau Applied Basic Research,No.23JCYBJC01800.
BACKGROUND Hepatocellular carcinoma(HCC)ranks as the sixth most common cancer and the third-leading cause of cancer-related deaths worldwide.The multidisciplinary tumor board(MDTB)has been recognized for improving out...
supported by Sichuan Province Central Government Guide Local Science and Technology Development Project(No.2023ZYD0169).
Background:Non-small cell lung cancer(NSCLC)is often accompanied by brain metastasis(BM),and the prognosis of patients with BM is poor.This study assesses the prognostic impact of BM in NSCLC patients with epidermal g...