PATHOGENESIS

作品数:1184被引量:6649H指数:39
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相关领域:医药卫生更多>>
相关作者:袁红张韶峰刘平白丽敏郑静晨更多>>
相关机构:北京中医药大学哈尔滨医科大学武警总医院温州医科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金广东省自然科学基金更多>>
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Age-dependent alpha-synuclein aggregation and Lewy body formation in Parkinson's disease
《Neural Regeneration Research》2025年第12期3533-3534,共2页Chun Chau Sung Kenny K.K.Chung 
supported by the Innovation and Technology Commission (ITCPD/17-9);the Hong Kong Research Grants Council,China (GRF16104517)(to KKKC)。
Parkinson's disease (PD) is a common degenerative disorder that is becoming increasingly prevalent because of the global aging population.The exact cause of the disorder is unknown;however,recent studies have suggeste...
关键词:PATHOGENESIS AGGREGATION BECOMING 
PI3K/AKT signaling and neuroprotection in ischemic stroke:molecular mechanisms and therapeutic perspectives
《Neural Regeneration Research》2025年第10期2758-2775,共18页Tianlong Liu Xiaolin Li Xiaowei Zhou Wei Chen Aidong Wen Minna Liu Yi Ding 
supported by the National Natural Science Foundation of China,Nos.82274313(to YD),82204746(to ML),82003982(to TL).
It has been reported that the PI3K/AKT signaling pathway plays a key role in the pathogenesis of ischemic stroke.As a result,the development of drugs targeting the PI3K/AKT signaling pathway has attracted increasing a...
关键词:apoptosis autophagy inflammation ischemic stroke NEUROPROTECTION oxidative stress PATHOGENESIS phosphatidylinositol 3-kinase protein kinase B THERAPEUTICS 
Gut virome and its emerging role in inflammatory bowel disease
《World Journal of Methodology》2025年第3期22-24,共3页Rahat Khatoon Khokhar Abdulqadir J Nashwan 
Inflammatory bowel disease(IBD)is a progressive multifactorial inflammatory disease of the gut.The cause of IBD is yet unknown.Some researchers have shown that genetic factors,environmental factors,and the gut microbi...
关键词:Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses 
Glycolytic dysregulation in Alzheimer's disease:unveiling new avenues for understanding pathogenesis and improving therapy
《Neural Regeneration Research》2025年第8期2264-2278,共15页You Wu Lijie Yang Wanrong Jiang Xinyuan Zhang Zhaohui Yao 
supported by the National Natural Science Foundation of China,No.82271214(to ZY);the Natural Science Foundation of Hubei Province of China,No.2022CFB109(to ZY)。
Alzheimer's disease poses a significant global health challenge owing to the progressive cognitive decline of patients and absence of curative treatments.The current therapeutic strategies,primarily based on cholinest...
关键词:Alzheimer’s disease glial cells GLYCOLYSIS neuronal metabolism PATHOGENESIS therapeutic targets 
Gut virome:New key players in the pathogenesis of inflammatory bowel disease
《World Journal of Methodology》2025年第2期27-43,共17页Helal F Hetta Rehab Ahmed Yasmin N Ramadan Hayam Fathy Mohammed Khorshid Mohamed M Mabrouk Mai Hashem 
Inflammatory bowel disease(IBD)is a chronic inflammatory illness of the intes-tine.While the mechanism underlying the pathogenesis of IBD is not fully under-stood,it is believed that a complex combination of host immu...
关键词:Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses 
Relationship between Helicobacter pylori infection and programmed death-ligand 1 in gastric cancer:A meta-analysis
《World Journal of Clinical Oncology》2025年第4期280-290,共11页Hong-Chang Yang Cheng-Feng Fu Li-Jun Qiao Gen-He Long Li-Fen Yang Biao Yao 
BACKGROUND Gastric cancer(GC)is one of the most common malignancies worldwide,and Helicobacter pylori(HP)infection is a well-established risk factor for its development.Programmed death-ligand 1(PD-L1)expression is a ...
关键词:Helicobacter pylori Gastric cancer Programmed cell death protein 1/programmed death-ligand 1 Immune checkpoint blockade therapy PATHOGENESIS 
Gene expression analysis in subcutaneous adipose tissue reveals a predominant influence of IncRNAs during growth
《Genes & Diseases》2025年第2期125-128,共4页Federica Reyy Letizia Messa Clarissa Berardao Alessia Mauri Gianvincenzo Zuccotti Cristina Cereda Stephana Carelli 
The adipose tissue is a crucial energy reservoir that can undergo significant changes during aging,impacting the pathogenesis of metabolic disorders,including obesity.1 Obesity affects individuals of all ages,with dif...
关键词:OBESITY PATHOGENESIS predominant 
Pathogenesis, diagnosis, and treatment of epilepsy: electromagnetic stimulation-mediated neuromodulation therapy and new technologies被引量:1
《Neural Regeneration Research》2025年第4期917-935,共19页Dian Jiao Lai Xu Zhen Gu Hua Yan Dingding Shen Xiaosong Gu 
supported by the National Natural Science Foundation of China,No.32130060(to XG).
Epilepsy is a severe,relapsing,and multifactorial neurological disorder.Studies regarding the accurate diagnosis,prognosis,and in-depth pathogenesis are crucial for the precise and effective treatment of epilepsy.The ...
关键词:DIAGNOSIS drug treatment ELECTROENCEPHALOGRAPHY epilepsy monitoring EPILEPSY nerve regeneration NEUROSTIMULATION non-drug interventions PATHOGENESIS prediction 
Genetic and environmental factors influencing Crohn’s disease
《World Journal of Gastrointestinal Surgery》2025年第3期1-5,共5页Ye-Hui Fan Ming-Wei Wang Yu-Ning Gao Wen-Mao Li Yan Jiao 
This editorial discusses Pellegrino and Gravina's essay.Crohn’s disease(CD)is a complex and multifactorial disease that is influenced by a combination of genetic and environmental factors.While genetic factors play a...
关键词:Crohn’s disease PATHOGENESIS Nucleotide-binding oligomerization domain-2 SMOKING Vitamin D 
Role of interleukins in the pathogenesis of coronary heart disease:A literature review
《World Journal of Cardiology》2025年第3期41-57,共17页Saira Rafaqat Azeem Azam Ramsha Hafeez Hamza Faseeh Maria Tariq Muhammad Asif Amber Arshad Iqra Noshair 
Interleukins(ILs),a subset of cytokines,play a critical role in the pathogenesis of coronary heart disease(CHD)by mediating inflammation.This review article summarizes the role of ILs such as IL-1,IL-2,IL-3,IL-4,IL-5,...
关键词:Coronary heart disease INTERLEUKINS Inflammation PATHOGENESIS 
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