AGGREGATION

作品数：949被引量：1357H指数：14
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Age-dependent alpha-synuclein aggregation and Lewy body formation in Parkinson's disease
《Neural Regeneration Research》2025年第12期3533-3534,共2页Chun Chau Sung Kenny K.K.Chung 
supported by the Innovation and Technology Commission (ITCPD/17-9);the Hong Kong Research Grants Council,China (GRF16104517)(to KKKC)。
Parkinson's disease (PD) is a common degenerative disorder that is becoming increasingly prevalent because of the global aging population.The exact cause of the disorder is unknown;however,recent studies have suggeste...
关键词：PATHOGENESIS AGGREGATION BECOMING 
Small heat shock protein B8:from cell functions to its involvement in diseases and potential therapeutic applications被引量：1
《Neural Regeneration Research》2025年第10期2872-2886,共15页Marta Chierichetti Riccardo Cristofani Valeria Crippa Veronica Ferrari Marta Cozzi Elena Casarotto Paola Pramaggiore Laura Cornaggia Guglielmo Patelli Ali Mohamed Margherita Piccolella Mariarita Galbiati Paola Rusmini Barbara Tedesco Angelo Poletti 
supported by:Fondazione Telethon-Italy(No.GGP19128 to AP);Fondazione Cariplo-Italy(No.2021-1544 to RC);Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica(AriSLA)-Italy(No.MLOpathy to AP;Target-RAN to AP);Association Française contre les Myopathies-France(AFM Telethon No.23236 to AP);Kennedy’s Disease Association-USA(2018 grant to RC;2020 grant to MG);Ministero dell’Universitàe della Ricerca(MIUR)-Italy(PRIN-Progetti di ricerca di interesse nazionale(No.2017F2A2C5 to AP;No.2022EFLFL8 to AP;No.2020PBS5MJ to VC;No.2022KSJZF5 to VC);PRIN-Progetti di ricerca di interesse nazionale-bando 2022,PNRR finanziato dall’Unione europea-Next Generation EU,componente M4C2,investimento 1.1(No.P2022B5J32 to RC and No.P20225R4Y5 to VC);CN3:RNA-Codice Proposta:CN_00000041;Tematica Sviluppo di terapia genica e farmaci con tecnologia a RNA(Centro Nazionale di Ricerca-CN3 National Center for Gene Therapy and Drugs based on RNA Technology to AP);Progetto Dipartimenti di Eccellenza(to DiSFeB);Ministero della Salute,Agenzia Italiana del Farmaco(AIFA)-Italy(Co_ALS to AP);Universitàdegli Studi di Milano(piano di sviluppo della ricerca(PSR)UNIMI-linea B(to RC and BT).
Heat shock protein family B(small)member 8(HSPB8)is a 22 kDa ubiquitously expressed protein belonging to the family of small heat shock proteins.HSPB8 is involved in various cellular mechanisms mainly related to prote...
关键词：AGGREGATION AUTOPHAGY cancer CHAPERONE chaperone-assisted selective autophagy cognitive impairment HSPB8 NEUROINFLAMMATION neuromuscular diseases therapy 
Navigating the pathways:TAR-DNA-binding-protein-43 aggregation,axonal transport,and local synthesis in amyotrophic lateral sclerosis pathology
《Neural Regeneration Research》2025年第10期2921-2922,共2页Ori Bar Avi Eran Perlson 
Neurons are highly polarized cells with axons reaching over a meter long in adult humans.To survive and maintain their proper function,neurons depend on specific mechanisms that regulate spatiotemporal signaling and m...
关键词：SYNTHESIS LOCAL AGGREGATION 
Aggregation‑Induced Emissive Scintillators:A New Frontier for Radiation Detection and Imaging
《Nano-Micro Letters》2025年第7期190-205,共16页Xinyi Li Jiafu Yu Yinghao Fan Yuting Gao Guangda Niu 
financial support from National Natural Science Foundation of China(No.22175156);the Fundamental Research Funds for the Central Universities,China University of Geosciences(Wuhan)(No.162301202692).
Aggregation-induced emission(AIE)is a unique phenomenon where certain organic materials exhibit enhanced luminescence in their aggregated states,overcoming the typical quenching observed in conventional organic materi...
关键词：Aggregation-induced emission SCINTILLATORS Radiation detection Radiation imaging 
Role of glutathione transferase in phase separation of FUS and TAF15 in neurons
《Neural Regeneration Research》2025年第7期1999-2000,共2页Kiyoung Kim 
supported by the BK21 FOUR(Fostering Outstanding Universities for Research)and the Basic Science Research Program through the National Research Foundation of Korea(NRF),funded by the Ministry of Education(MOE)and the Ministry of Science and ICT(MSIT)(NRF-2022R1A2C1004204,RS-2023-00219563,2023-DD-UP-0007);by the Soonchunhyang University Research Fund(to KK)。
Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord,leading to muscle weakness,paralysis,and ultimately death(C...
关键词：DEGENERATION FUS AGGREGATION 
GD-YOLO:A Network with Gather and Distribution Mechanism for Infrared Image Detection of Electrical Equipment
《Computers, Materials & Continua》2025年第4期897-915,共19页Junpeng Wu Xingfan Jiang 
Science and Technology Department of Jilin Province(No.20200403075SF);Education Department of Jilin Province(No.JJKH20240148KJ).
As technologies related to power equipment fault diagnosis and infrared temperature measurement continue to advance,the classification and identification of infrared temperature measurement images have become crucial ...
关键词：Infrared image detection aggregation and distribution mechanism sample imbalance strategy lightweight structure 
An Efficient Instance Segmentation Based on Layer Aggregation and Lightweight Convolution
《Computers, Materials & Continua》2025年第4期1041-1055,共15页Hui Jin Shuaiqi Xu Chengyi Duan Ruixue He Ji Zhang 
supported by Science and Technology Research Youth Project of Chongqing Municipal Education Commission(No.KJQN202301104);Cooperative Project between universities in Chongqing and Affiliated Institutes of Chinese Academy of Sciences(No.HZ2021011);Chongqing Municipal Science and Technology Commission Technology Innovation and Application Development Special Project(No.2022TIAD-KPX0040);Action Plan for Quality Development of Chongqing University of Technology Graduate Education(Grant No.gzlcx20242014).
Instance segmentation is crucial in various domains,such as autonomous driving and robotics.However,there is scope for improvement in the detection speed of instance-segmentation algorithms for edge devices.Therefore,...
关键词：Automatic driving CONVOLUTION deep learning real-time instance segmentation 
LMSA:A Lightweight Multi-Key Secure Aggregation Framework for Privacy-Preserving Healthcare AIoT
《Computer Modeling in Engineering & Sciences》2025年第4期827-847,共21页Hyunwoo Park Jaedong Lee 
supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.NRF-2022R1C1C2012463).
Integrating Artificial Intelligence of Things(AIoT)in healthcare offers transformative potential for real-time diagnostics and collaborative learning but presents critical challenges,including privacy preservation,com...
关键词：Secure aggregation LIGHTWEIGHT federated learning 
Efficient UV emission from carbon dots derived from a green-tea extract
《Nano Research》2025年第4期516-525,共10页Henry Opoku Junkai Ren Xin Zhou Peijuan Zhang Shi Tang Dongfeng Dang Ludvig Edman Jia Wang 
J.C.Kempes Minnes Stipendiefond(SMK-21-0015 and SMK-1956);the Swedish Research Council(2019-02345,2020-04437,and 2021-04778);Bertil&Britt Svenssons stiftelse for belysningsteknik(2021 host-14 and 2022 host-31);the Knut and Alice Wallenberg Foundation for a Proof of Concept grant(KAW 2022.0381);the Wallenberg Initiative Materials Science for Sustainability(WISE)funded by the Knut and Alice Wallenberg Foundation(WISE-AP01-D02);the European Union through an ERC Advanced Grant(ERC,InnovaLEC,101096650).
Emissive carbon dots(CDs)that are synthesized from biomass can be highly sustainable,but the number of reported biomass-derived CDs that emit in the ultraviolet(UV)range is small.Moreover,current commercial UV-emittin...
关键词：carbon dots ultraviolet(UV)emission biomass aggregation-induced-emission cell proliferation inhibitor 
Heuristic Feature Engineering for Enhancing Neural Network Performance in Spatiotemporal Traffic Prediction
《Computers, Materials & Continua》2025年第3期4219-4236,共18页Bin Sun Yinuo Wang Tao Shen Lu Zhang Renkang Geng 
supported by the Shandong Province Higher Education Young Innovative Talents Cultivation Programme Project:TJY2114;Jinan City-School Integration Development Strategy Project:JNSX2023015;the Natural Science Foundation of Shandong Province:ZR2021M F074.
Traffic datasets exhibit complex spatiotemporal characteristics,including significant fluctuations in traffic volume and intricate periodical patterns,which pose substantial challenges for the accurate forecasting and...
关键词：Machine learning deep learning traffic time series prediction forecasting AGGREGATION 
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