BACTERIOPHAGE

作品数:84被引量:144H指数:6
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相关领域:医药卫生生物学更多>>
相关作者:张帅领张智慧唐瑞杨勇波邓瑞玲更多>>
相关机构:石河子大学吉林大学广东海洋大学华中师范大学更多>>
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相关基金:国家自然科学基金中国博士后科学基金中央高校基本科研业务费专项资金湖北省自然科学基金更多>>
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Gut virome and its emerging role in inflammatory bowel disease
《World Journal of Methodology》2025年第3期22-24,共3页Rahat Khatoon Khokhar Abdulqadir J Nashwan 
Inflammatory bowel disease(IBD)is a progressive multifactorial inflammatory disease of the gut.The cause of IBD is yet unknown.Some researchers have shown that genetic factors,environmental factors,and the gut microbi...
关键词:Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses 
Gut virome:New key players in the pathogenesis of inflammatory bowel disease
《World Journal of Methodology》2025年第2期27-43,共17页Helal F Hetta Rehab Ahmed Yasmin N Ramadan Hayam Fathy Mohammed Khorshid Mohamed M Mabrouk Mai Hashem 
Inflammatory bowel disease(IBD)is a chronic inflammatory illness of the intes-tine.While the mechanism underlying the pathogenesis of IBD is not fully under-stood,it is believed that a complex combination of host immu...
关键词:Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses 
The phage anti-restriction induced system:new insights into bacterial immunity and bacteriophage escape strategies
《Signal Transduction and Targeted Therapy》2024年第11期4753-4754,共2页Yi Zhong Volker M.Lauschke 
funded by the Swedish Research Council[2021-02801 and 2023-03015];the Robert Bosch Foundation.
Two recent publications in Nature reveal the detailed structural mechanisms underlying the recognition of infection by the bacterial Phage Anti-Restriction Induced System(PARIS).1,2 These findings are important as the...
关键词:IMMUNITY SYSTEM finding 
Visible-light-sensitive AgCu nanocomposites for sustainable inactivation of virus
《Journal of Materials Science & Technology》2024年第28期74-79,共6页Jianfei Xie Ziyu Wan Xing Zhou Hongmei Li Yu Chen Yinglong Duan Min Liu 
supported by the Wisdom Accumulation and Talent Cultivation Project of the Third Xiangya Hospital of Central South University(No.BJ202205);the National Natural Science Foundation of China(Grant No.22376222);the Central South University Research Programme of Advanced Interdisciplinary Studies(Grant No.2023QYJC012);the Natural Science Foundation of Hunan Province(Grant No.2021JJ30864).
The coronavirus disease 2019(COVID-19)caused a large number of deaths and serious economic losses.Safety precautions and effective measures are urgently demanded to control the virus spread in public places.Owing to t...
关键词:Ag_(2)Cu_(2)O_(3) AgCuO_(2) Qβbacteriophage Work function 
Insertion sequence transposition activates antimycobacteriophage immunity through an Isr2-silenced lipid metabolism gene island
《mLife》2024年第1期87-100,共14页Yakun Li Yuyun Wei Xiao Guo Xiaohui Li Lining Lu Lihua Hu Zheng-Guo He 
supported by the National Natural Science Foundation of China(32230002);the National Key R&D Program of China(2020YFA0907200),and the Ba-Gui Scholar Program of Guangxi(To Z.G.H).
Insertion sequences(ISs)exist widely in bacterial genomes,but their roles in the evolution of bacterial antiphage defense remain to be clarified.Here,we report that,under the pressure of phage infection,the IS1o96 tra...
关键词:antiphage defense BACTERIOPHAGE gene island insertion sequence MYCOBACTERIA 
A novel depolymerase specifically degrades the K62-type capsular polysaccharide of Klebsiella pneumoniae
《One Health Advances》2024年第1期317-326,共10页Yuqing Pan Huagen Chen Ruijing Ma Yongqin Wu Heyuan Lun Aixi Wang Kai He Jingran Yu Ping He 
funded by the the National Key Research and development Project of China(grant no.2022YFA1304300);National Natural Science Foundation of China(grant no.81971896).
Carbapenem-resistant Klebsiella pneumoniae(CRKP)is emerging as an imminent threat to worldwide public health because of its high level of antimicrobial resistance,which can result in severe and challenging-to-treat in...
关键词:Klebsiella pneumoniae BACTERIOPHAGE Capsule depolymerase 
Defense and anti-defense mechanisms of bacteria and bacteriophages
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2024年第3期181-196,共16页Xiaoqing WANG Sebastian LEPTIHN 
This work was supported by the Western Medicine Program of the Zhejiang Provincial Health Commission(No.2024KY592);the Fundamental Research Funds for Central Universities of the Central South University(No.2-2050205-19-361),China.
In the post-antibiotic era,the overuse of antimicrobials has led to a massive increase in antimicrobial resistance,leaving medical doctors few or no treatment options to fight infections caused by superbugs.The use of...
关键词:BACTERIOPHAGE Phage resistance Abortive infection Phage therapy 
Co-production of 1,3-propanediol and phage phiKpS2 from the glycerol fermentation by Klebsiella pneumoniae
《Bioresources and Bioprocessing》2024年第1期610-620,共11页Suyang Duan Zhirong Zhang Xiaoli Wang Yaqin Sun Yuesheng Dong Lina Ren Lili Geng Zhilong Xiu 
Funding was provided by the National Natural Science Foundation of China(Grant No.22078042).
As an alternative to antibiotics in response to antimicrobial-resistant infections,bacteriophages(phages)are garnering renewed interest in recent years.However,the massive preparation of phage is restricted using trad...
关键词:Klebsiella pneumonia 1 3-Propanediol BACTERIOPHAGE CO-PRODUCTION Salting-out extraction 
Translating bacteriophage-derived depolymerases into antibacterial therapeutics:Challenges and prospects被引量:1
《Acta Pharmaceutica Sinica B》2024年第1期155-169,共15页Honglan Wang Yannan Liu Changqing Bai Sharon Shui Yee Leung 
This work was supported by the University Grants Committee,Hong Kong SAR Government(No.14112921,China).The support of HKPFS from the University Grants Committee to HonglanWang was greatly acknowledged.
Predatory bacteriophages have evolved a vast array of depolymerases for bacteria capture and deprotection.These depolymerases are enzymes responsible for degrading diverse bacterial surface carbohydrates.They are expl...
关键词:Phage-derived polysaccharide depolymerases Bacteriophage proteins Bacterial capsules Polysaccharide capsules Antibiotic resistance Biofilms Antibacterial therapy Antimicrobial adjuvants Combination treatment 
CRISPR-Cas9 mediated phage therapy as an alternative to antibiotics
《Animal Diseases》2023年第4期231-241,共11页Fikre Birhanu Balcha Sultan Abda Neja 
Inappropriate use of antibiotics is globally creating public health hazards associated with antibiotic resistance.Bacteria often acquire antibiotic resistance by altering their genes through mutation or acquisition of...
关键词:CRISPR-Cas9 BACTERIOPHAGE Phagemid Antibiotic-resistant 
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