MYCOBACTERIA

作品数：40被引量：55H指数：5
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相关作者：李王平刘冠更多>>
相关机构：第四军医大学唐都医院北京市结核病胸部肿瘤研究所中国科学院广州生物医药与健康研究院更多>>
相关期刊：《国际内科双语杂志（中英文）》《Chinese Medical Journal》《Advances in Microbiology》《mLife》更多>>
相关基金：国家自然科学基金陕西省科技攻关计划北京市科技新星计划更多>>
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Insertion sequence transposition activates antimycobacteriophage immunity through an Isr2-silenced lipid metabolism gene island
《mLife》2024年第1期87-100,共14页Yakun Li Yuyun Wei Xiao Guo Xiaohui Li Lining Lu Lihua Hu Zheng-Guo He 
supported by the National Natural Science Foundation of China(32230002);the National Key R&D Program of China(2020YFA0907200),and the Ba-Gui Scholar Program of Guangxi(To Z.G.H).
Insertion sequences(ISs)exist widely in bacterial genomes,but their roles in the evolution of bacterial antiphage defense remain to be clarified.Here,we report that,under the pressure of phage infection,the IS1o96 tra...
关键词：antiphage defense BACTERIOPHAGE gene island insertion sequence MYCOBACTERIA 
Late recurrence in surgically managed pediatric atypical mycobacterial lymphadenitis:A case report and review of the literature
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2023年第4期357-364,共8页Katerina Green Alexa Denton Jeffrey Graves Joshua Wiedermann 
Objective:The purpose of this study is to identify existing literature on recurrent atypical mycobacterial cervicofacial lymphadenitis to augment our understanding of a unique patient who presented to our tertiary‐ca...
关键词：atypical mycobacteria case report CURETTAGE nontuberculosis mycobacteria pediatric lymphadenitis pediatric lymphadenopathy recurrent nontuberculosis mycobacterial infection 
Optimization of Technical Parameters for Detecting Mycobacteria in Hospital Wastewater in Tropical Urban Areas: The Case of the City of Abidjan (Côte d’Ivoire)
《Open Journal of Medical Microbiology》2023年第3期195-206,共12页Cissé Souleymane Coulibaly-Kalpy Julien Vakou N’dri Sabine Assohoiun Egomli Stanislas Ouattara Mohamed Baguy Kouamé Kintossou Ambroise Diané Kouao Maxime Ettien Money Marcelle Nguessan Felix Kouassi Dosso Mireille 
The loads of organic matter, microorganisms, detergents and antibiotics in liquid hospital effluents make them complex environments, raising numerous health and ecological questions. Investigations of mycobacteria in ...
关键词：Hospital Wastewater MYCOBACTERIUM DECONTAMINATION Löwenstein Jensen Medium Growth Temperature 
Multivalent Display of Lipophilic DNA Binders for Dual-Selective Anti-Mycobacterium Peptidomimetics with Binary Mechanism of Action
《CCS Chemistry》2022年第11期3573-3586,共14页Jianxue Wang Junfeng Song Xianhui Chen Rey-Ting Guo Yingjie Wang Guopu Huang Nan Zheng Peilei Hu Xinxin Feng Yugang Bai 
This research was made possible as a result of the start-up funding from Hunan University,as a part of China’s Fundamental Research Funds for the Central Universities,the funding from the National Natural Science Foundation of China(grant nos.21877033,92163127,Y.B.,21807031,22177031,X.F.);the funding from the Natural Science Foundation of Hunan Province(grant no.2021JJ30088,Y.B.,2020JJ4177,X.F.);the Open Funding Project of the State Key Laboratory of Biocatalysis and Enzyme Engineering(Hubei University,SKLBEE2019003,X.F.).
We made oligoamidine-based peptidomimetics highly specific for mycobacteria eradication by introducing and arraying lipophilic DNA binding motifs on macromolecular backbones.The short poly(amidino-phenylindole)(PAPI)s...
关键词：PEPTIDOMIMETIC MYCOBACTERIA antimicrobial membrane disruption DNA binding 
PAM-Expanded Streptococcus thermophilus Cas9 C-to-T and C-to-G Base Editors for Programmable Base Editing in Mycobacteria
《Engineering》2022年第8期67-77,共11页Hongyuan Zhang Yifei Zhang Wei-Xiao Wang Weizhong Chen Xia Zhang Xingxu Huang Wei Chen Quanjiang Ji 
supported by the National Natural Science Foundation of China(21922705(to Quanjiang Ji),91753127(to Quanjiang Ji),and 2207783(to Quanjiang Ji));the Shanghai Committee of Science and Technology(19QA1406000(to Quanjiang Ji));the Emergency Key Program of Guangzhou Laboratory(EKPG21-18(to Quanjiang Ji));General Program of Jiangsu Health Committee Foundation(M2020019(to Wei Chen))。
New therapeutic strategies for the rapid and effective treatment of drug-resistant tuberculosis are highly desirable,and their development can be drastically accelerated by facile genetic manipulation methods in Mycob...
关键词：CRISPR Cas9 Mycobacterium tuberculosis Genome editing Base editing 
Assessment of the Quality of Life of Patients with Mycobacterial Pulmonary Diseases
《Open Journal of Respiratory Diseases》2022年第2期56-63,共8页Khadidia Ouattara Bocar Baya Dianguina Soumaré Tenin Kanouté Mohamed Tolofodie Kafui Komla Gaglo Koudemon Salif Koné Bassirou Diarra Yaya Sadio Sarro Yacouba Toloba Mamoudou Maiga 
Introduction: Mycobacteria pulmonary diseases are chronic illnesses with various impacts on patients’ health status, and wellbeing. These diseases currently represent a global health issue due to increasing burdens a...
关键词：Quality of Life MYCOBACTERIA LUNG 
Mesenchymal-epithelial Transition Factor Regulates Monocyte Function during Mycobacterial Infection via Indoleamine 2,3-dioxygenase被引量：1
《Current Medical Science》2022年第2期407-416,共10页Bing-fen YANG Fei ZHAI Hong-juan AN Jing JIANG Zhi-hong CAO Yan-hua LIU Jin-wen SU Ruo WANG Xiao-xing CHENG 
This study was supported by the Thirteen-Fifth Mega-Scientific Project on“Prevention and Treatment of AIDS,Viral Hepatitis and Other Infectious Diseases”(No.2017ZX10201301-007-002);the National Natural Science Foundation of China(No.81571961 and No.82072233);the 309th Hospital(No.2017ZD-007).
Objective Mycobacterium tuberculosis(Mtb),the causative agent of tuberculosis(TB),causes an estimated 1.6 million human deaths annually,but the pathogenesis of TB remains unclear.Immunity plays a critical role in the ...
关键词：MONOCYTES MYCOBACTERIA mesenchymal-epithelial transition factor indoleamine 2 3-dioxygenase 
Long-term case-fatality rate of nontuberculous mycobacterial disease in people living with HIV被引量：1
《Infectious Diseases of Poverty》2022年第1期47-55,共9页Jingjing Hu Ling Gu Yueming Shao Renfang Zhang Tangkai Qi Jianjun Sun Zhenyan Wang Wei Song Yang Tang Jiangrong Wang Shuibao Xu Junyang Yang Yinzhong Shen Li Liu Jun Chen Hongzhou Lu 
Shanghai Commission of Science and Technology(20MC1920100 and 21Y11901200);Shanghai key Infectious Disease Project(shslczdzk01102);Shanghai Municipal Health Commission(GWV-10.1-XK02);development fund for Shanghai talents(2020089);Shanghai "Rising stars of Medical Talent" Youth Development Program(No. 2019-72)。
Background:Few data are available regarding the long-term case-fatality rate(CFR)among people living with HIV(PLWH)with nontuberculous mycobacteria(NTM)disease.The aim of this study is to analyze the long-term CFR in ...
关键词：HIV/AIDS Nontuberculous MYCOBACTERIA CASE-FATALITY rate Risk FACTOR 
Prevalence of non-tuberculosis mycobacteria among samples deposited from the National Tuberculous Reference Laboratory of Iran(2011-2018)被引量：1
《Asian Pacific Journal of Tropical Medicine》2021年第10期451-456,共6页Saman Ayoubi Parissa Farnia Poopak Farnia Jafar Aghajani Jalaledin Ghanavi Ali Akbar Velayati 
supported by funding from the Mycobacteriology Research Center,National Tuberculosis and Lung Research Institute(NRITLD),Masih Daneshvari Hospital(Grant No.16597)
Objective:To investigate the prevalence of non-tuberculosis mycobacteria(NTM)among the samples deposited from the National Tuberculosis Reference Laboratory of Iran between 2011 and 2018.Methods:The study evaluated th...
关键词：Diagnosis Iran Non-tuberculosis Mycobacterium PREVALENCE 
Drug resistance and pathogenic spectrum of patients coinfected with nontuberculous mycobacteria and human-immunodeficiency virus in Chengdu, China被引量：7
《Chinese Medical Journal》2019年第11期1293-1297,共5页Dong-Mei Wang Yi Liao Qing-Feng Li Ma Zhu Gui-Hui Wu Yuan-Hong Xu Jing Zhong Jia Luo Ying-Jie Li 
Background:Human-immunodeficiency virus (HIV) infection is increasing worldwide and nontuberculous mycobacteria (NTM) is an established microbiologic cause of pulmonary disease,lymphadenitis,and disseminated disease i...
关键词：Clinical features DRUG resistance HIV MYCOBACTERIUM avium-intracellulare infection MYCOBACTERIUM kansasii Nontuberculous MYCOBACTERIA 
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