DRUG

作品数:1783被引量:4004H指数:23
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相关领域:医药卫生更多>>
相关作者:唐神结肖和平潘勤韩德民顾之燕更多>>
相关机构:中国药科大学复旦大学北京大学中国科学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金中国博士后科学基金更多>>
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Soluble epoxide hydrolase:a next-generation drug target for Alzheimer's disease and related dementias
《Neural Regeneration Research》2025年第9期2585-2586,共2页Andrew Gregory Chengyun Tang Fan Fan 
Alzheimer's disease(AD)and Alzheimer's diseaserelated dementias(ADRD)represent a significant public health challenge,with projections indicating a substantial increase in affected individuals due to the aging global p...
关键词:ALZHEIMER POPULATION DRUG 
Understanding antituberculosis drug-induced hepatotoxicity:Risk factors and effective management strategies in the pediatric population
《World Journal of Clinical Pediatrics》2025年第2期47-55,共9页Pooja Semwal Manjit Kaur Saini Moinak Sen Sarma 
Antituberculosis drug-induced hepatotoxicity(ATDIH)is a significant concern while managing pediatric tuberculosis.There is limited data on pediatric ATDIH,and much of the management practices are extrapolated from adu...
关键词:Antituberculosis therapy DRUG Liver INJURY Isonaizid RIFAMPICIN PYRAZINAMIDE 
Research Report on Cell Quantum Medicine:Theory,Practice,and Prospects
《Journal of Clinical and Nursing Research》2025年第4期331-342,共12页Zhigang Hu Liran Xu Xiaohong Lv Xiangbo Yu 
This paper is Taiji medicine based on the theory of traditional Chinese medicine and traditional medicine,and the core of Taiji medicine is“wave-particle duality of qi and field”,which is a life science based on cel...
关键词:Cellular quantum medicine Disease characteristic frequency Drug characteristic frequency Life radiation energy medicine Life cell quantum 
Reasons for discontinuing tirzepatide in randomized controlled trials:A systematic review and meta-analysis
《World Journal of Diabetes》2025年第4期284-296,共13页Abul Bashar Mohammad Kamrul-Hasan Joseph M Pappachan Deep Dutta Lakshmi Nagendra Mohammad Shafi Kuchay Nitin Kapoor 
BACKGROUND Despite therapeutic benefits,discontinuation of tirzepatide is common in randomized controlled trials(RCTs)due to adverse events(AEs)and other causes.No previous systematic reviews have explored the reasons...
关键词:Tirzepatide Drug adherence Study drug discontinuation Adverse events Withdrawal by the study subjects 
DARG:An integrated knowledge base for analyzing addictive drug-related genes
《Genes & Diseases》2025年第2期140-142,共3页Xu Wang Bei Yun Zihan Zhang Xiaoxi Wang Yifan Wu Yubo Hu Shiyi Fang Junjie Lv Lina Chen Wan Li 
supported by the Natural Science Foundation of Heilongjiang Province,China (No.LH2021F043);the National Natural Science Foundation of China (No.61702141).
Drug addiction is a complex brain disease closely related to the expression and methylation of many genes.Differential genes can influence addiction,and some key differential genes may have a significant impact on the...
关键词:DRUGS DIC ADDICTION 
Pure drug nanomedicines-where we are?
《Chinese Journal of Natural Medicines》2025年第4期385-409,共25页Yaoyao Lai Bing Xie Wanting Zhang Wei He 
supported by the National Natural Science Foundation of China(Nos.82073782 and 82241002)。
Pure drug nanomedicines(PDNs)encompass active pharmaceutical ingredients(APIs),including macromolecules,biological compounds,and functional components.They overcome research barriers and conversion thresholds associat...
关键词:Pure drug nanomedicines Drug nanocrystals Drug-drug cocrystals Antibody-drug conjugates Drug nanoparticles Nanobodies 
The effects of Urgently Needed Overseas Drugs on the launch delay of new drugs in China
《Pharmacoeconomics and Policy》2025年第1期15-20,共6页Xingyue Zhu Yang Chen 
The Chinese drug agency has issued the Urgently Needed Overseas Drug(UNOD)lists since 2018,which allows drugs to be approved based on overseas trial data,to address drug delays.We aimed to evaluate the effects of the ...
关键词:Drug lag Launch delay Drug access Instrumental variables 
Injectable drug-loaded thermosensitive hydrogel delivery system for protecting retina ganglion cells in traumatic optic neuropathy
《Regenerative Biomaterials》2025年第1期178-194,共17页Lei Wang Yan Jiang Yili Yao Yudan Deng Zhiqiang Liu Jiangtao Ding Wenwen Wang Hao Chen Kaihui Nan Lingli Li 
supported by Natural Science Foundation of Zhejiang Province(LY24C100002);Wenzhou Science and Technology Foundation(Y20210266);Engineering Research Center of Clinical Functional Materials and Diagnosis&Treatment Devices of Zhejiang Province(WIUCASK20004);Zhejiang Engineering Research Center for Tissue Repair Materials(WIUCASZZXF21002);Joint Medical Research Center of Xiangshan Hospital Affiliated to Wenzhou Medical University and Wenzhou Institute of Chinese Academy of Sciences(WIUCAS)(XSZX09);startup grant from WIUCAS(WIUCASQD2023022,WIUCASQD2022035).
Currently,generalized therapy for traumatic optic neuropathy(TON)is lacking.Various strategies have been developed to protect and regenerate retinal ganglion cells(RGCs)after TON.Intravitreal injection of supplements ...
关键词:TON retinal ganglion cells thermosensitive hydrogel CNTF TA 
Prehospital critical care drug-therapy and 30-day mortality in patients with acute respiratory disease
《World Journal of Emergency Medicine》2025年第1期43-50,共8页Jesús Jurado-Palomo JoséLuis Martín-Conty Begoña Polonio-López Cristina Rivera Picón Raúl López-Izquierdo Carlos del Pozo Vegas Pedro Ángel de Santos Castro Ancor Sanz-García Francisco Martín-Rodríguez 
supported by the Institute of Health Carlos Ⅲ (Spain);co-financed by the European Union (DTS23/00010) for FMR。
BACKGROUND: Prehospital medication is a reality, and the role of these therapies must be explored to assess their validity, especially for acute respiratory diseases, which are usually associated with increased morbid...
关键词:Drug-therapy MEDICATION PREHOSPITAL MORTALITY Emergency medical services 
创新药物递送系统的研究进展与展望
《药学进展》2025年第1期1-3,共3页吴锦慧 
1创新药物递送系统概述药物递送系统(drug delivery system,DDS)是指在空间、时间及剂量上全面调控药物在生物体内分布的技术体系。其旨在将适量的药物在恰当的时机递送到正确的位置,并完成符合预期的释放以提高药物疗效、降低药物不良...
关键词:药物递送系统 药物不良反应 小分子药物 药物疗效 DRUG 研究进展与展望 递送 利用效率 
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