RIFAMPICIN

作品数：75被引量：155H指数：6
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Understanding antituberculosis drug-induced hepatotoxicity:Risk factors and effective management strategies in the pediatric population
《World Journal of Clinical Pediatrics》2025年第2期47-55,共9页Pooja Semwal Manjit Kaur Saini Moinak Sen Sarma 
Antituberculosis drug-induced hepatotoxicity(ATDIH)is a significant concern while managing pediatric tuberculosis.There is limited data on pediatric ATDIH,and much of the management practices are extrapolated from adu...
关键词：Antituberculosis therapy DRUG Liver INJURY Isonaizid RIFAMPICIN PYRAZINAMIDE 
Liposome of a synergistic combination of HDP-mimicking polymer and rifampicin for treating bacterial infections in aquaculture via oral administration
《Science China Materials》2025年第4期1259-1270,共12页Haowen Yu Luhang Chen Yueming Wu Wenhui Dai Minzhang Chen Yuan Chen Longqiang Liu Jiangzhou Wang Xinqi Huang Kang Chen Runhui Liu 
supported by the National Natural Science Foundation of China(T2325010,52203162,22075078);the National Key Research and Development Program of China(2022YFC2303100);the Fundamental Research Funds for the Central Universities(JKVD1241029,JKD01241701);the Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism(Shanghai Municipal Education Commission)。
The extensive use of antibiotics in high-density aquaculture has accelerated the emergence of antibiotic-resistant bacteria.The presence of antibiotics in water and soil,and their transmission through the food chain e...
关键词：liposomes oral administration AQUACULTURE synergistic combinations Vibrio infections 
Ferroptosis and Intrinsic Drug-induced Liver Injury by Acetaminophen and Other Drugs: A Critical Evaluation and Historical Perspective
《Journal of Clinical and Translational Hepatology》2024年第12期1057-1066,共10页Hartmut Jaeschke Anup Ramachandran 
supported in part by National Institute of Diabetes and Digestive and Kidney Diseases grants R01 DK102142(HJ)and R01 DK125465(AR),as well as by National Institute of General Medical Sciencesfunded Liver Disease COBRE grants P20 GM103549(HJ)and P30 GM118247(HJ).
Drug-induced hepatotoxicity is a significant clinical issue worldwide.Given the limited treatment options for these liver injuries,understanding the mechanisms and modes of cell death is crucial for identifying novel ...
关键词：Drug hepatotoxicity ACETAMINOPHEN Lipid peroxidation Oxidative stress Ferroptosis Glutathione peroxidase 4 Erastin Ferrostatin-1 METHOTREXATE RIFAMPICIN ISONIAZID Natural products 
Activation of pregnane X receptor sensitizes alcoholic steatohepatitis by transactivating fatty acid binding protein 4
《Acta Pharmaceutica Sinica B》2024年第11期4776-4788,共13页Yiwen Zhang Bingfang Hu Shaoxing Guan Pan Li Yingjie Guo Pengfei Xu Yongdong Niu Yujin Li Ye Feng Jiewen Du Jun Xu Xiuchen Guan Jingkai Gu Haiyan Sun Min Huang 
National Natural Science Foundation of China(Grant Nos.82020108031,82404752,81730103,81573507 and 81973398);National Key Research and Development Program(Grant Nos.2017YFC0909300 and 2016YFC0905000,China);Guangdong Provincial Key Laboratory of Construction Foundation(Grant Nos.2017B030314030 and 2020B1212060034,China);Science and Technology Program of Guangzhou(Grant No.201607020031,China);National Engineering and Technology Research Center for New drug Druggability Evaluation Seed Program of Guangdong Province(Grant No.2017B090903004,China);111 project(Grant No.B16047,China);Guangdong Basic and Applied Basic Research Foundation(Grant Nos.2022A1515012549 and 2023A1515012667,China);Marine Medicine Innovation Platform for the Integration of Production and Education Project of Guangdong Provincial Education Department(No.2021CJPT014,China);Shenzhen Stability Support Project for Colleges and Universities(No.20220814205518001,China);Shenzhen Sustainable Development Project(No.KCXFZ20230731094501002,China).
Alcoholic steatohepatitis (ASH) is a liver disease characterized by steatosis, inflammation, and necrosis of the liver tissue as a result of excessive alcohol consumption. Pregnane X receptor (PXR) is a xenobiotic nuc...
关键词：Alcoholic steatohepatitis Fatty acid binding protein 4 Pregnane X receptor Alcoholic liver disease ANDROGRAPHOLIDE Nuclear receptorLiver injury RIFAMPICIN 
Feasibility of Integrating Leprosy Post-Exposure Prophylaxis with Single-Dose Rifampicin (LPEP) into Routine Leprosy Control Program in Bukedi and Teso Regions in Uganda
《Advances in Infectious Diseases》2024年第3期563-580,共18页Rose Kengonzi Turyahabwe Stavia Lisa Gerwing-Adima Nyote Ronald Kamara Vincent Consolata Mbambara Yusuf Wanyama Buyinza Godfrey Tinyo Daniel Mulwani Elisa Namuyode Damali Aloket Francis 
Background: World Health Organization recommends the implementation of contact tracing and Leprosy Post Exposure prophylaxis (LPEP) to interrupt the chain of transmission. To accelerate the uptake of this recommendati...
关键词：LEPROSY Post Exposure Prophylaxis Single Dose Rifampicin 
Tuberculosis in kidney transplant candidates and recipients
《World Journal of Transplantation》2024年第3期59-69,共11页Pallavi Prasad Sourabh Sharma Subashri Mohanasundaram Anupam Agarwal Himanshu Verma 
Tuberculosis(TB)is the leading cause of infectious mortality and morbidity in the world,second only to coronavirus disease 2019.Patients with chronic kidney disease and kidney transplant recipients are at a higher ris...
关键词：TUBERCULOSIS Latent Antitubercular therapy Kidney transplantation Donor Interferon-gamma release assays TUBERCULIN RIFAMPICIN ISONIAZID 
Analysis of Factors Influencing Plasma Concentration of Rifampicin in Patients with Pulmonary Tuberculosis
《感染控制(英文)》2024年第1期68-77,共10页Jia Zhou Ai-Xian Huang Hong-Fa Tan Yu-Ting Ma Yan Liang Chun-Xiong Su 
supported by Xingning District Scientific Research and Technology Development Project(#2021A11).
Objective To analyze the factors influencing the rifampicin blood concentration in patients with tuberculosis and provide a scientific basis for clinical physicians to formulate anti-tuberculosis treatment plans.Metho...
关键词：HEMODIALYSIS RIFAMPICIN plasma concentration pulmonary tuberculosis influencing factors 
Contribution to the Study of Resistance to Anti-Tuberculosis Drugs in the Mycobacterium tuberculosis Complex Isolated at the National Laboratory of Clinical Biology and Public Health in Bangui in the Central African Republic in 2022: Case of Rifampicin
《Journal of Tuberculosis Research》2023年第4期162-172,共11页Clotaire Donatien Rafaï Max Namzeka Ernest Lango-Yaya Romaric Oscar Tibet Kada Oscar Senzongo Ndimakamoko Serge Henri Gbazi Le Bon Bondom Christian Maucler Pamatika Boniface Koffi Alain Le Faou 
Microscopy-positive and drug-resistant pulmonary tuberculosis (MPT+) is one of the most feared diseases due to the cost of its management and the associated mortality. The GeneXpert, a new molecular test, is in greate...
关键词：GeneXpert RESISTANCE Mycobacterium tuberculosis Bangui 
Synergistic impacts of rifampicin and doxorubicin against thioacetamide-induced hepatocellular carcinoma in rats
《Liver Research》2023年第4期352-360,共9页Zahraa R.Elshahawy Entsar A.Saad Rana R.El-Sadda 
Background and aims:Combination therapy is a promising new strategy that has been proposed to increase the efficacy of cancer treatment.We aimed to investigate the anti-cancer activity of rifampicin monotherapy and it...
关键词：Hepatocellular carcinoma(HCC) RIFAMPICIN DOXORUBICIN Bcl-2-associated X protein(Bax) CASPASE Protein 53(p53) THIOACETAMIDE 
A comparative study of adsorption behavior of rifampicin,streptomycin,and ibuprofen contaminants from aqueous solutions onto chitosan:Dynamic interactions,kinetics,diffusions,and mechanisms被引量：1
《Emerging Contaminants》2023年第1期20-32,共13页Ensan Waatriah E.S.Shahrin Nur Alimatul Hakimah Narudin Nurulizzatul Ningsheh MShahri Muhammad Nur Jun-Wei Lim Muhammad Roil Bilad Abdul Hanif Mahadi Jonathan Hobley Anwar Usman 
Dr.Jonathan Hobley is grateful to National Cheng Kung University's NCKU90 distinguished visiting scholar program for hosting his research;MOST for providing research funding under project number 111-2222-E-006-007.
Adsorptive removal and dynamic interaction of three different pharmaceutical pollutants,namely rifampicin(RIF),streptomycin(STM),and ibuprofen(IBU)onto chitosan were systematically investigated using a batch adsorptio...
关键词：Adsorption RIFAMPICIN STREPTOMYCIN IBUPROFEN CHITOSAN Mud-carb shells 
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