THIOACETAMIDE

作品数:42被引量:140H指数:7
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相关领域:医药卫生更多>>
相关作者:林文政更多>>
相关机构:中国医药大学台湾大学中国人民解放军陆军军医大学更多>>
相关期刊:《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》《Chemical Research in Chinese Universities》《World Journal of Hepatology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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Dysregulation of bile acid signal transduction causes neurological dysfunction in cirrhosis rats
《World Journal of Hepatology》2025年第3期140-151,共12页Chao Ren Li Cha Shu-Yue Huang Guo-Hui Bai Jin-Hui Li Xin Xiong Yu-Xing Feng Dui-Ping Feng Long Gao Jin-Yu Li 
Supported by the National Natural Science Foundation of China,No.82200650;the Key Research and Development Projects of Shanxi Province,No.202102130501014;the Natural Science Foundation of Shanxi Province,No.202203021211021,No.202203021212046,and No.20210302123258.
BACKGROUND The pathogenesis of hepatic encephalopathy(HE)remains unclear,and the classical theory of ammonia toxicity lacks sufficient justification.AIM To investigate the potential of bile acids as intervention targe...
关键词:Hepatic encephalopathy Total bile acid THIOACETAMIDE G protein-coupled bile acid receptor 1 Liver cirrhosis 
Bifunctional passivation by lewis-base molecules for efficient printable mesoscopic perovskite solar cells
《Journal of Energy Chemistry》2024年第9期177-184,共8页Hang Yang Jianhong Zhao Xiaodong Ren Tong Zhou Henbing Zhang Weilong Zhang Jin Zhang Guangzhi Hu Yuming Zhang Wen-Hua Zhang Qingju Liu 
funded by the Yunnan Yunling Scholars Project,the National Natural Science Foundation of China(No.51562038);the Young-Middle-Aged Academic and Technical Leaders Reserve Talent Project in Yunnan Province(No.202005AC160015);the Yunnan Basic Applied Research Project(No.202101AT070013).
Printable mesoscopic perovskite solar cells(PM-PSCs)possess notable merits in terms of cost-effectiveness,easy manufacturing,and large scale applications.Nevertheless,the absence of a hole transport layer contributes ...
关键词:Perovskite solarcells Carbon electrode THIOACETAMIDE Interfacial passivation 
Thioacetamide Additive Homogenizing Zn Deposition Revealed by In Situ Digital Holography for Advanced Zn Ion Batteries
《Nano-Micro Letters》2024年第6期261-275,共15页Kaixin Ren Min Li Qinghong Wang Baohua Liu Chuang Sun Boyu Yuan Chao Lai Lifang Jiao Chao Wang 
supported by the National Natural Science Foundation of China(No.22075115);Natural Science Foundation of Jiangsu Province(No.BK20211352);Joint Funds of the National Natural Science Foundation of China(No.U2141201);Natural Science Foundation(No.22KJA430005)of Jiangsu Education Committee of China;Postgraduate Research and Practice Innovation Program of Jiangsu Normal University(No.2021XKT0296).
Zinc ion batteries are considered as potential energy storage devices due to their advantages of low-cost,high-safety,and high theoretical capacity.However,dendrite growth and chemical corrosion occurring on Zn anode ...
关键词:Digital holographic microscopy In situ observation Electrode/electrolyte interface Zn dendrites Screening electrolyte additives 
Dual neovascular targets of vascular endothelial growth factor receptors and platelet-derived growth factor receptor ameliorate thioacetamide induced liver fibrosis in rats
《Portal Hypertension & Cirrhosis》2024年第1期1-13,共13页Bin Xiong Yaowei Bai Jiacheng Liu Tongqiang Li Yingliang Wang Chen Zhou 
National Natural Science Foundation of China,Grant/Award Number:81873917。
Aims:Neovascularization plays a crucial role in liver fibrosis(LF),and blocking vascular endothelial growth factor receptors(VEGFR)has been shown to improve fibrosis.The aim of our study was to investigate the role of...
关键词:ANTIANGIOGENESIS apatinib donafenib FIBROSIS 
AGK2 pre-treatment protects against thioacetamide-induced acute liver failure via regulating the MFN2-PERK axis and ferroptosis signaling pathway被引量:2
《Hepatobiliary & Pancreatic Diseases International》2024年第1期43-51,共9页Qing-Qi Zhang Qian Chen Pan Cao Chun-Xia Shi Lu-Yi Zhang Lu-Wen Wang Zuo-Jiong Gong 
supported by the grant from the National Natural Science Foundation of China (82070609)
Background:Acute liver failure(ALF)is an unpredictable and life-threatening critical illness.The pathological characteristic of ALF is massive necrosis of hepatocytes and lots of inflammatory cells infiltration which ...
关键词:SIRT2 inhibitor AGK2 Acute liver failure MFN2 Ferroptosis 
Synergistic impacts of rifampicin and doxorubicin against thioacetamide-induced hepatocellular carcinoma in rats
《Liver Research》2023年第4期352-360,共9页Zahraa R.Elshahawy Entsar A.Saad Rana R.El-Sadda 
Background and aims:Combination therapy is a promising new strategy that has been proposed to increase the efficacy of cancer treatment.We aimed to investigate the anti-cancer activity of rifampicin monotherapy and it...
关键词:Hepatocellular carcinoma(HCC) RIFAMPICIN DOXORUBICIN Bcl-2-associated X protein(Bax) CASPASE Protein 53(p53) THIOACETAMIDE 
Hydroxysafflor yellow A protects against thioacetamide-induced liver fibrosis in rats via suppressing proinflammatory/fibrogenic mediators and promoting hepatic stellate cell senescence and apoptosis
《Asian Pacific Journal of Tropical Biomedicine》2023年第8期348-358,共11页Sayed H.Seif el-Din Olfat A.Hammam Shahira M.Ezzat Samira Saleh Marwa M.Safar Walaa H.El-Maadawy Naglaa M.El-Lakkany 
funded by Theodore Bilharz Research Institute (grant number:ID-MS-99/A,Principal investigator:Naglaa M.El-Lakkany).
Objective:To evaluate the effect of hydroxysafflor yellow A(HSYA)on thioacetamide-induced liver fibrosis.Methods:Thioacetamide was administered to rats intraperitoneally in doses of 200 mg/kg twice a week for 12 weeks...
关键词:Hydroxysafflor yellow A THIOACETAMIDE Hepatic stellate cells Inflammatory markers Liver fibrosis p21 α-SMA APOPTOSIS 
Chrysanthemum indicum ethanol extract attenuates hepatic stellate cell activation in vitro and thioacetamide-induced hepatofibrosis in rats被引量:2
《Asian Pacific Journal of Tropical Biomedicine》2021年第11期500-509,共10页Yun-Jin Chae Sushruta Koppula Myong-Ki Kim Tony Yoon MinDong Song 
supported by Konkuk University in 2020。
Objective:To investigate the antifibrotic effects of Chrysanthemum indicum ethanol extract(CIEE)against activated hepatic stellate cells(HSC)and thioacetamide(TAA)-induced hepatofibrosis in rats.Methods:Cell viability...
关键词:Chrysanthemum indicum Fibrosis HEPATOPROTECTIVE HYDROXYPROLINE THIOACETAMIDE 
Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats被引量:5
《World Journal of Gastroenterology》2020年第28期4094-4107,共14页Wei Su Yang Tai Shi-Hang Tang Yan-Ting Ye Chong Zhao Jin-Hang Gao Bi-Guang Tuo Cheng-Wei Tang 
the National Natural Science Fund of China,No.U1702281,No.81670551,and No.81873584.
BACKGROUND Endoplasmic reticulum(ER)stress is an important mechanism in the progression of chronic and acute liver diseases,especially in the progression and recovery of liver fibrosis.Excessive and long-term ER stres...
关键词:Liver fibrosis Endoplasmic reticulum stress CELECOXIB CYCLOOXYGENASE-2 CCAAT/enhancer binding protein homologous protein Apoptosis 
Generation of induced secretome from adipose-derived stem cells specialized for disease-specific treatment:An experimental mouse model被引量:2
《World Journal of Stem Cells》2020年第1期70-86,共17页Ok-Hee Kim Ha-Eun Hong Haeyeon Seo Bong Jun Kwak Ho Joong Choi Kee-Hwan Kim Joseph Ahn Sang Chul Lee Say-June Kim 
Supported by National Research Foundation of Korea,No.NRF-2015R1C1A1A02036931
BACKGROUND Recently,the exclusive use of mesenchymal stem cell(MSC)-secreted molecules,named as the secretome,have been evaluated for overcoming the limitations of cell-based therapy while maintaining its advantages.A...
关键词:Adipose-derived stem cells Disease-specificity Mesenchymal stem cells SECRETOME Peroxiredoxin-1 THIOACETAMIDE Toxic hepatic failure 
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