HEPATOPROTECTIVE

作品数:113被引量:299H指数:9
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相关领域:医药卫生更多>>
相关作者:阮丽萍冷沥钦余伯阳朱丹妮更多>>
相关机构:中国人民解放军中国药科大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划福建省自然科学基金更多>>
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Protective Effects of Pomegranate and Its Bioactive Components on Hepatic Disease
《Medicinal Plant》2025年第1期81-90,共10页Hong LI Erziya MAI Wenxin ZHENG Yanting HU Zhongrui ZHANG Puyang GONG Jian GU 
Supported by the National Natural Science Foundation of China(81573563);Scientific and Technological Innovation Team for Qinghai-Tibetan Plateau Research in Southwest Minzu University(2024CXTD16);the Sichuan Provincial Administration of Traditional Chinese Medicine Innovation Team Project(2023ZD05).
By summarizing the pharmacological effects of pomegranate extract and its active components,such as punicalagin,punicalin,gallic acid,ellagic acid,caffeic acid,and chlorogenic acid,it is found that the extract exhibit...
关键词:POMEGRANATE Hepatic disease HEPATOPROTECTIVE Functional food Mechanism of action Pharmacology effect 
The Impact of SARS-CoV-2 on Liver Diseases and Potential Phytochemical Treatments
《Infectious Microbes & Diseases》2024年第4期177-188,共12页Dhanvee Balaji Ranjith Balakrishnan Dhasarathdev Srinivasan Rajasekaran Subbarayan Rupendra Shrestha Nityanand Srivastava Ankush Chauhan 
The COVID-19 pandemic,caused by the SARS-CoV-2 virus,has brought about numerous challenges.One of these challenges is the impact of SARS-CoV-2 on the liver.Although this virus primarily affects the lungs,it can induce...
关键词:COVID-19 nonalcoholic fatty liver disease alcohol-induced liver injury hepatocellular carcinoma PHYTOCHEMICALS HEPATOPROTECTIVE 
Polysaccharides from Chinese herbal medicine:a review on the hepatoprotective and molecular mechanism
《Chinese Journal of Natural Medicines》2024年第1期4-14,共11页LI Jifeng GUO Haolin DONG Ying YUAN Shuo WEI Xiaotong ZHANG Yuxin DONG Lu WANG Fei BAI Ting YANG Yong 
This work was supported by the National Natural Science Foundation of China(Nos.81900532 and 81700523);the Central Guidance Local Science and Technology Development Project of Dalian City(YANG Yong)。
Polysaccharides,predominantly extracted from traditional Chinese medicinal herbs such as Lycium barbarum,Angelica sinensis,Astragalus membranaceus,Dendrobium officinale,Ganoderma lucidum,and Poria cocos,represent prin...
关键词:POLYSACCHARIDES HEPATOPROTECTIVE Chinese herbal medicine MECHANISM 
Magnesium Enhances the Hepatorenal Protective Effects of Lippia multiflora Aqueous Leaves Extract in Streptozotocin-Diabetic Rats
《Journal of Biosciences and Medicines》2023年第10期35-45,共11页Yapo Fulgence Allo Viviane Jocelyne Zannou-Tchoko Kouamé Hermann Yéboué Brou André Konan Jacques Yao Datté 
Purpose: This study was conducted in order to evaluate the antidiabetic effects of the aqueous extract of Lippia multiflora supplemented with magnesium on some biochemical markers of the kidneys and liver in type 2 di...
关键词:Lippia multiflora Diabetes STREPTOZOTOCIN NEPHROPROTECTIVE HEPATOPROTECTIVE 
MgIG Attenuates Oxaliplatin-induced Hepatotoxicity through Suppression of Connexin 43 in Hepatic Stellate Cells被引量:1
《Journal of Clinical and Translational Hepatology》2023年第3期584-594,共11页Yuzhu Cao Yawen Xia Yufei Wang Hang Shi Yuanyuan Wu Yin Lu 
the Open Project Program of Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica(No.JKLPSE201501);the Open Project of Chinese Materia Medica First-Class Discipline of Nanjing University of Chinese Medicine(No.2020YLXK20);the Science and Technology Development Foundation of Nanjing Medical University(No.NMUB2019186).
Background and Aims:Oxaliplatin is widely used in can-cer chemotherapy with adverse effects such as liver toxicity.Magnesium isoglycyrrhizinate(MgIG)has hepatoprotective effects,but the underlying mechanism remains el...
关键词:Magnesium isoglycyrrhizinate HEPATOPROTECTIVE 18α-Glycyrrhetinic acid Mitochondrial dysfunction Hepatic stellate cell Connexin 43. 
Development and Evaluation of Stable Paracetamol Loaded Solid Dispersion with Enhanced Analgesic and Hepatoprotective Property
《Pharmacology & Pharmacy》2023年第4期123-143,共21页Ashim Kumar Milon Kumar Ghosh Mst. Boby Aktar Bithy Md. Rafiqul Islam Khan Md. Monimul Huq Mir Imam Ibne Wahed Ranjan Kumar Barman 
Paracetamol (PCM) is enlisted in the WHO model list as an essential medicine for pain and palliative care, but at overdose, it causes hepatic damage. This study was designed to assess the analgesic efficacy and hepato...
关键词:PARACETAMOL Solid Dispersion DISSOLUTION Analgesic Activity HEPATOCYTE Particle Surface Property Stability 
Voacanga grandifolia(Miq.)Rolfe protects against alcohol-induced liver toxicity in rats
《Asian Pacific Journal of Tropical Biomedicine》2022年第12期504-511,共8页Lal Chand Pal Shivankar Agrawal Arti Gautam 
Objective:To evaluate the ethanol extract of Voacanga grandifolia for hepatoprotective and antioxidant potential against ethanol-induced liver toxicity in rats.Methods:Sprague-Dawley rats were administered ethanol(7 g...
关键词:Antioxidant Ethanol-induced toxicity HEPATOPROTECTIVE Hepatic markers Voacanga grandifolia 
Discovery of possible hepatoprotective components from lychee pulp phenolic extract by online knockout methods
《Food Bioscience》2022年第6期587-593,共7页Xuchao Jia Lihong Dong Yejie Wen Fei Huang Jianwei Chi Ruifen Zhang 
The project funded by Guangdong Province’s key research and development program(2020B0202080003),China;Guangzhou science and technology project(201903010051,202103000055),China;the Guangdong special support program(2019BT02N112),China;the Special fund for scientific innovation strategy construction of high level Academy of Agriculture Science(R2017YJYB2006,R2020PY-JG011,202108TD),China.
Lychee pulp phenolic extract (LPPE) possessed protective effects against nonalcoholic fatty liver disease (NAFLD), while the specific components concerned were unclear. In this study, twelve major components in LPPE w...
关键词:Lychee pulp phenolic extract Hepatocyte steatosis Antioxidant Online knockout 
Antioxidant, hepatoprotective and nephroprotective activities of Gazania rigens against carbon tetrachloride-induced hepatotoxicity and nephrotoxicity in rats
《Traditional Medicine Research》2022年第5期29-39,共11页Alshymaa Abdel-Rhman Gomaa Mamdouh Nabil Samy Eman Zekry Attia Mina Ezzat Attya Michael Atef Fawzy Samar Yehia Desoukey Mohamed Salah Kamel 
Objective:The current study investigated the efficacy of total ethanolic extract and various fractions of Gazania rigens to protect against carbon tetrachloride-induced liver and kidney damage in rats and evaluated th...
关键词:Asteraceae Gazania rigens ANTIOXIDANT HEPATOPROTECTIVE NEPHROPROTECTIVE 
Hepatoprotective drugs for prevention of liver injury resulting from anti-tuberculosis treatment:A meta-analysis of cohort studies被引量:1
《Infectious Medicine》2022年第3期154-162,共9页Dong Wang Xiao-ling Cai Xu Lin Jing Zheng Yun-li Wu Xian-e Peng 
supported by grants from the National Natural Science Foundation of China(grant number 82172249);the Natural Science Foundation of Fujian Province(No.2019J01316,2020J01607).
Background:The incidence of liver injury caused by anti-tuberculous(TB)drugs is very high.However,owing to a lack of sufficient evidence,preventive use of hepatoprotective drugs is not yet recommended.Therefore,we aim...
关键词:Hepatoprotective drug TUBERCULOSIS Liver injury META-ANALYSIS 
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