Supported by the National Natural Science Foundation of China(81573563);Scientific and Technological Innovation Team for Qinghai-Tibetan Plateau Research in Southwest Minzu University(2024CXTD16);the Sichuan Provincial Administration of Traditional Chinese Medicine Innovation Team Project(2023ZD05).
By summarizing the pharmacological effects of pomegranate extract and its active components,such as punicalagin,punicalin,gallic acid,ellagic acid,caffeic acid,and chlorogenic acid,it is found that the extract exhibit...
The COVID-19 pandemic,caused by the SARS-CoV-2 virus,has brought about numerous challenges.One of these challenges is the impact of SARS-CoV-2 on the liver.Although this virus primarily affects the lungs,it can induce...
This work was supported by the National Natural Science Foundation of China(Nos.81900532 and 81700523);the Central Guidance Local Science and Technology Development Project of Dalian City(YANG Yong)。
Polysaccharides,predominantly extracted from traditional Chinese medicinal herbs such as Lycium barbarum,Angelica sinensis,Astragalus membranaceus,Dendrobium officinale,Ganoderma lucidum,and Poria cocos,represent prin...
Purpose: This study was conducted in order to evaluate the antidiabetic effects of the aqueous extract of Lippia multiflora supplemented with magnesium on some biochemical markers of the kidneys and liver in type 2 di...
the Open Project Program of Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica(No.JKLPSE201501);the Open Project of Chinese Materia Medica First-Class Discipline of Nanjing University of Chinese Medicine(No.2020YLXK20);the Science and Technology Development Foundation of Nanjing Medical University(No.NMUB2019186).
Background and Aims:Oxaliplatin is widely used in can-cer chemotherapy with adverse effects such as liver toxicity.Magnesium isoglycyrrhizinate(MgIG)has hepatoprotective effects,but the underlying mechanism remains el...
Paracetamol (PCM) is enlisted in the WHO model list as an essential medicine for pain and palliative care, but at overdose, it causes hepatic damage. This study was designed to assess the analgesic efficacy and hepato...
Objective:To evaluate the ethanol extract of Voacanga grandifolia for hepatoprotective and antioxidant potential against ethanol-induced liver toxicity in rats.Methods:Sprague-Dawley rats were administered ethanol(7 g...
The project funded by Guangdong Province’s key research and development program(2020B0202080003),China;Guangzhou science and technology project(201903010051,202103000055),China;the Guangdong special support program(2019BT02N112),China;the Special fund for scientific innovation strategy construction of high level Academy of Agriculture Science(R2017YJYB2006,R2020PY-JG011,202108TD),China.
Lychee pulp phenolic extract (LPPE) possessed protective effects against nonalcoholic fatty liver disease (NAFLD), while the specific components concerned were unclear. In this study, twelve major components in LPPE w...
Objective:The current study investigated the efficacy of total ethanolic extract and various fractions of Gazania rigens to protect against carbon tetrachloride-induced liver and kidney damage in rats and evaluated th...
supported by grants from the National Natural Science Foundation of China(grant number 82172249);the Natural Science Foundation of Fujian Province(No.2019J01316,2020J01607).
Background:The incidence of liver injury caused by anti-tuberculous(TB)drugs is very high.However,owing to a lack of sufficient evidence,preventive use of hepatoprotective drugs is not yet recommended.Therefore,we aim...